{"id":"W4384069979","doi":"10.1093/noajnl/vdad071.049","title":"TARGETING CANCER STEM CELLS WITH A CDK2 INHIBITOR IN GLIOBLASTOMA","year":2023,"lang":"en","type":"article","venue":"Neuro-Oncology Advances","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Cancer research; Stem cell; CDK inhibitor; Cyclin-dependent kinase; Cancer stem cell; Biology; Carcinogenesis; Cancer; Cell cycle; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009718914,0.0004034927,0.0003915321,0.0004986642,0.0001374478,0.0003323076,0.0002253876,0.0002168246,0.001175773],"category_scores_gemma":[0.00005296703,0.0001068625,0.0002438342,0.0003170445,0.000123841,0.0001504872,0.0001672848,0.0003957066,0.0003026007],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005450454,"about_ca_system_score_gemma":0.0003479263,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002044157,"about_ca_topic_score_gemma":0.005033465,"domain_scores_codex":[0.9999421,0.000006795319,0.000005169453,0.00001033797,0.00001778257,0.00001793642],"domain_scores_gemma":[0.9999771,0.000003064906,0.000004768034,0.00000197559,0.000004833481,0.000008191677],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005281719,0.0003657448,0.000793738,0.0002601901,0.00004496199,0.0002058664,0.00002325257,0.001520822,0.9724869,0.0003405997,0.001001411,0.02242837],"study_design_scores_gemma":[0.0001517774,0.001879319,0.002555677,0.00001736142,0.00005984812,0.0003777815,0.00002306913,0.002632076,0.9828941,0.00009900079,0.009300938,0.000009138101],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9707149,0.01606217,0.004389721,0.0003872017,0.0001028738,0.0002134816,0.001518691,0.0003228035,0.006288094],"genre_scores_gemma":[0.9834188,0.008392302,0.003436681,0.0001685978,0.00001894825,0.0001054956,0.001174887,0.00002427076,0.003259843],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002044157,"threshold_uncertainty_score":0.0040645,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006734176557242824,"score_gpt":0.2582711645331096,"score_spread":0.2515369879758667,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}