{"id":"W4384072197","doi":"10.1038/s41586-023-06362-4","title":"Immune sensing of food allergens promotes avoidance behaviour","year":2023,"lang":"en","type":"article","venue":"Nature","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":147,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Nautical Research Society","funders":"National Center for Advancing Translational Sciences; National Institute of Arthritis and Musculoskeletal and Skin Diseases; NGM Biopharmaceuticals; University of California, San Diego; Yale University; National Institutes of Health; National Institute of Allergy and Infectious Diseases; Food Allergy Research and Education","keywords":"Immunology; Immune system; Immunoglobulin E; Food allergy; Biology; Allergen; Sensitization; Allergy; Antigen; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001765469,0.000371429,0.0002250721,0.0002761403,0.0000995361,0.0002395552,0.0001627518,0.0003094179,0.00151245],"category_scores_gemma":[0.0001534203,0.0001610948,0.0002994647,0.00007718636,0.0002912817,0.0001892482,0.0003396716,0.0006835642,0.0003339483],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000143204,"about_ca_system_score_gemma":0.00009006543,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001791318,"about_ca_topic_score_gemma":0.0004624043,"domain_scores_codex":[0.9998338,0.00002684049,0.000007835837,0.00004167978,0.00004995601,0.00003977519],"domain_scores_gemma":[0.9997491,0.00003199143,0.00008734746,0.00003259669,0.00002111005,0.00007779283],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005622996,0.00001997426,0.0006069674,0.00001822154,0.000003847816,0.00003599568,0.00001289615,0.00001156463,0.9981759,0.00004475401,0.00002571115,0.0009879952],"study_design_scores_gemma":[0.0000364509,0.002176039,0.2065297,0.0000438695,0.00004481545,0.001617346,0.0001427618,0.001332682,0.7837997,0.0005554926,0.003695287,0.00002571538],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949368,0.001235685,0.001854409,0.000107661,0.00002916126,0.00001122084,0.00007952125,0.00009920809,0.001646303],"genre_scores_gemma":[0.9958524,0.0006314379,0.001327141,0.00008944758,0.00001801958,0.00001655271,0.0001300388,0.00002839088,0.001906613],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00151245,"threshold_uncertainty_score":0.0050596,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008093958265857836,"score_gpt":0.2260925588801808,"score_spread":0.217998600614323,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}