{"id":"W4384072197","doi":"10.1038/s41586-023-06362-4","title":"Immune sensing of food allergens promotes avoidance behaviour","year":2023,"lang":"en","type":"article","venue":"Nature","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":147,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Nautical Research Society","funders":"National Center for Advancing Translational Sciences; National Institute of Arthritis and Musculoskeletal and Skin Diseases; NGM Biopharmaceuticals; University of California, San Diego; Yale University; National Institutes of Health; National Institute of Allergy and Infectious Diseases; Food Allergy Research and Education","keywords":"Immunology; Immune system; Immunoglobulin E; Food allergy; Biology; Allergen; Sensitization; Allergy; Antigen; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001205595,0.00009647302,0.0001825101,0.00007591431,0.00008407531,0.000003311604,0.0001088905,0.0008652954,0.0002867696],"category_scores_gemma":[0.00004746465,0.00008473358,0.00007354883,0.0001977343,0.0000709411,0.00002103135,0.00005995054,0.001006203,0.0001868525],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007909393,"about_ca_system_score_gemma":0.0000204043,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002036033,"about_ca_topic_score_gemma":0.00004199747,"domain_scores_codex":[0.9993984,0.00003845996,0.0001618481,0.0001621962,0.00002904428,0.0002101053],"domain_scores_gemma":[0.9996042,0.00003744074,0.00007696681,0.000202977,0.00006918494,0.000009222043],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002539814,0.00003776243,0.0004398693,0.00003373843,0.00006645297,0.000007730124,0.0003768459,0.000001608119,0.9902663,0.0007395835,0.005984204,0.002020464],"study_design_scores_gemma":[0.0008507828,0.0002443396,0.04028119,0.000072331,0.00003921938,0.000043339,0.0002161143,0.00001048609,0.8609768,0.0002782963,0.09676933,0.0002177322],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989269,0.007606635,0.000008115278,0.0004201581,0.0008564661,0.0001137588,0.00006312944,0.00009878216,0.001563965],"genre_scores_gemma":[0.9899302,0.00007314653,0.00009703358,0.00004879733,0.00002640232,0.000001291811,0.0001430419,0.00001336188,0.009666701],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1292895,"threshold_uncertainty_score":0.6673951,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008093958265857836,"score_gpt":0.2260925588801808,"score_spread":0.217998600614323,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}