{"id":"W4384081595","doi":"10.17952/36eps.2022.272","title":"Studies Towards the Chemical Synthesis of Sonic Hedgehog","year":2022,"lang":"en","type":"article","venue":"","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Agència de Gestió d'Ajuts Universitaris i de Recerca","keywords":"Sonic hedgehog; Computer science; Hedgehog; Chemistry; Biochemistry; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005050335,0.0004686898,0.0002295851,0.0005322688,0.0004339774,0.0003500274,0.0005035414,0.0003357661,0.001666465],"category_scores_gemma":[0.0005748193,0.000224368,0.0003504067,0.0003812894,0.0005188212,0.0005633502,0.0003541693,0.0007355998,0.000667009],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000666616,"about_ca_system_score_gemma":0.0006912691,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001686923,"about_ca_topic_score_gemma":0.001383404,"domain_scores_codex":[0.9998018,0.00006023813,0.00001406862,0.00003336458,0.00004947215,0.00004102802],"domain_scores_gemma":[0.9997792,0.00007584751,0.00003336984,0.00003346982,0.00004921692,0.00002889938],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002740576,0.0001221216,0.0002441772,0.0003261487,0.00003695081,0.0003173453,0.0001472565,0.001141717,0.9778054,0.008035113,0.0002653594,0.01128438],"study_design_scores_gemma":[0.00001285346,0.0002805499,0.0002751711,0.000008648472,0.00001983186,0.0001539565,0.00003421502,0.000424501,0.9900023,0.0004872487,0.008292419,0.000008276555],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8472389,0.01341049,0.08948623,0.001103509,0.0004243745,0.0003615521,0.0007885889,0.000273162,0.04691322],"genre_scores_gemma":[0.9550123,0.009305808,0.02277273,0.0001925189,0.00009829154,0.00009159717,0.0007527543,0.00007511261,0.01169913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001686923,"threshold_uncertainty_score":0.005574882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0432711255004255,"score_gpt":0.2884409134880584,"score_spread":0.2451697879876329,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}