{"id":"W4384108168","doi":"10.21203/rs.3.rs-3117230/v1","title":"Isatuximab–pomalidomide–dexamethasone vs. pomalidomide–dexamethasone in patients with relapsed and refractory multiple myeloma: final overall survival analysis","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital; University Hospital","funders":"","keywords":"Pomalidomide; Dexamethasone; Multiple myeloma; Medicine; Internal medicine; Oncology; Refractory (planetary science); Lenalidomide; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004366588,0.00080216,0.002445627,0.0004694832,0.0002827683,0.001198188,0.0007558801,0.0007609613,0.001593576],"category_scores_gemma":[0.001946519,0.0003082146,0.005088284,0.0004467398,0.0003624745,0.0007498487,0.0005095282,0.001919848,0.0002484415],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009627793,"about_ca_system_score_gemma":0.0008477115,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007239687,"about_ca_topic_score_gemma":0.001818249,"domain_scores_codex":[0.9985265,0.0007329607,0.0001051967,0.0002468277,0.0001568317,0.0002315898],"domain_scores_gemma":[0.9982697,0.0006528437,0.0003917877,0.0001316074,0.0001146778,0.0004394007],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8407068,0.003252321,0.09053036,0.0004879938,0.01176589,0.0001800958,0.0001575489,0.004450348,0.003358449,0.0002290916,0.002045992,0.04283514],"study_design_scores_gemma":[0.1536045,0.348652,0.4425004,0.0002440111,0.02314411,0.0005626598,0.0004564051,0.02107964,0.003665274,0.001431334,0.004493009,0.000166611],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994939,0.002938461,0.0002780822,0.0001892002,0.00007828565,0.0001501708,0.0006914518,0.00001974754,0.0007156846],"genre_scores_gemma":[0.9975068,0.0003691336,0.000231906,0.0001734018,0.0000859783,0.0001051698,0.001183349,0.000005583551,0.0003386266],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004366588,"threshold_uncertainty_score":0.02309304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09119818203104472,"score_gpt":0.3774056283804285,"score_spread":0.2862074463493838,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}