{"id":"W4384199792","doi":"10.21203/rs.3.rs-3152536/v1","title":"WITHDRAWN: Metformin and exercise reduce miR-133a expression in skeletal muscles of diabetic rats","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Metformin; Medicine; Internal medicine; Endocrinology; Diabetes mellitus; Skeletal muscle","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001597888,0.0004922553,0.0005232872,0.0005072027,0.0001920641,0.0004688985,0.000402049,0.000714561,0.0154299],"category_scores_gemma":[0.0003441902,0.0001985814,0.000409231,0.0003690812,0.0004297997,0.0004535427,0.0003151934,0.001092438,0.002218342],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002037498,"about_ca_system_score_gemma":0.0003789869,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001363446,"about_ca_topic_score_gemma":0.001043989,"domain_scores_codex":[0.9997626,0.0000163775,0.00002628298,0.00005946546,0.00008585685,0.00004942655],"domain_scores_gemma":[0.999725,0.00005576227,0.00008201833,0.00003161793,0.00003309554,0.00007245205],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006318889,0.0003203509,0.001593138,0.0002955943,0.00007571786,0.0004669839,0.00006761611,0.0002407599,0.9663033,0.0007633084,0.003909242,0.01964509],"study_design_scores_gemma":[0.0004935836,0.001556803,0.05873801,0.00005873365,0.0002111013,0.0008086879,0.0003413931,0.001781333,0.9214477,0.0009463297,0.0135708,0.000045573],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9771516,0.001737073,0.005049867,0.001811141,0.001716909,0.00003264198,0.006028423,0.0007377013,0.005734716],"genre_scores_gemma":[0.9136536,0.002021729,0.005343202,0.0009031816,0.0003779299,0.0001613136,0.007107313,0.0004274791,0.07000422],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0154299,"threshold_uncertainty_score":0.0516181,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0409957024208128,"score_gpt":0.3618154819380433,"score_spread":0.3208197795172305,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}