{"id":"W4384281932","doi":"10.1186/s40824-023-00406-6","title":"Open source board based acoustofluidic transwells for reversible disruption of the blood–brain barrier for therapeutic delivery","year":2023,"lang":"en","type":"article","venue":"Biomaterials Research","topic":"Microfluidic and Bio-sensing Technologies","field":"Engineering","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ministry of Agriculture","funders":"Institute of Hydrobiology; Engineering and Physical Sciences Research Council; Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Blood–brain barrier; Open source; Chemistry; Neuroscience; Computer science; Biomedical engineering; Medicine; Biology; Central nervous system; Operating system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002579948,0.0004247927,0.0001751427,0.0002619587,0.0001340179,0.0003539712,0.0003661451,0.0005426141,0.001187248],"category_scores_gemma":[0.0003044344,0.0001634942,0.0003051196,0.0001426239,0.000250229,0.0005010747,0.000234496,0.000654497,0.0005216144],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002021749,"about_ca_system_score_gemma":0.0001615494,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00015769,"about_ca_topic_score_gemma":0.0004659158,"domain_scores_codex":[0.9997392,0.0000191041,0.00002263753,0.00005999329,0.0001309815,0.00002808503],"domain_scores_gemma":[0.9997455,0.00005870108,0.00008621977,0.00003222148,0.00005406028,0.00002327822],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000009963922,0.00001829213,0.00004678223,0.0000368119,0.00000236219,0.00003705713,0.00001450147,0.0001041392,0.9963929,0.0001851434,0.0001059522,0.003046076],"study_design_scores_gemma":[0.000007746948,0.0001618717,0.0009243709,0.000005454339,0.00001153353,0.0001822527,0.00001450518,0.002854904,0.9902627,0.00007195202,0.005490127,0.00001235595],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6679947,0.005625495,0.3157372,0.0005087569,0.000856958,0.0002838859,0.0006326011,0.00175622,0.006604128],"genre_scores_gemma":[0.8808039,0.003063779,0.109143,0.0001483917,0.00008648224,0.00024816,0.0003922491,0.0000812551,0.006032789],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001187248,"threshold_uncertainty_score":0.003971696,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09516782132470145,"score_gpt":0.3427301456093947,"score_spread":0.2475623242846932,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}