{"id":"W4384338991","doi":"10.1158/2159-8290.c.6742664","title":"Data from Spectrum of Response to Platinum and PARP Inhibitors in Germline <i>BRCA</i>–Associated Pancreatic Cancer in the Clinical and Preclinical Setting","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"Ministry of Science, Technology and Space; Hebrew University of Jerusalem; Deutsches Krebsforschungszentrum; Tel Aviv University; AstraZeneca","keywords":"Cancer research; In vivo; Pancreatic cancer; Medicine; Olaparib; PARP inhibitor; Poly ADP ribose polymerase; Cancer; Internal medicine; Oncology; Biology; Gene; Polymerase; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009904352,0.000211725,0.0004481934,0.0005055445,0.0001783366,0.0004953371,0.0002070856,0.0003267929,0.001715269],"category_scores_gemma":[0.001104066,0.0001263373,0.0003640356,0.0005361844,0.0003375536,0.0003263667,0.0002282382,0.0005817994,0.0003882095],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003539223,"about_ca_system_score_gemma":0.0002177314,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005666945,"about_ca_topic_score_gemma":0.0008520526,"domain_scores_codex":[0.9995968,0.00009594653,0.00006197362,0.00009199104,0.0001093954,0.00004395392],"domain_scores_gemma":[0.9986632,0.000469024,0.0003293519,0.0001916074,0.0001478746,0.0001989109],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.02022088,0.001394543,0.3921679,0.0006688089,0.0005593053,0.001154507,0.0005008582,0.004276564,0.4916171,0.000525042,0.00481357,0.08210073],"study_design_scores_gemma":[0.0005363176,0.02387089,0.7911158,0.00004686811,0.0006558213,0.007307196,0.0005436026,0.00295123,0.1565313,0.0003206427,0.0160756,0.00004471948],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"dataset","genre_scores_codex":[0.9923115,0.001883972,0.0005692295,0.0000948005,0.00001115303,0.00004385728,0.002359568,0.00004775969,0.0026781],"genre_scores_gemma":[0.9955459,0.0005489836,0.0002967647,0.00007918658,0.000008496545,0.00004248941,0.002946867,0.00001093515,0.000520447],"genre_candidate":"dataset","genre_consensus":null,"teacher_disagreement_score":0.001715269,"threshold_uncertainty_score":0.005738139,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1483739682886275,"score_gpt":0.4534822820816188,"score_spread":0.3051083137929913,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}