{"id":"W4384463921","doi":"10.58931/cht.2022.1214","title":"Chimeric antigen receptor T-cell therapy for relapsed and refractory large B-cell lymphoma","year":2022,"lang":"en","type":"article","venue":"Canadian Hematology Today","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Chemoimmunotherapy; Medicine; Rituximab; Lymphoma; Vincristine; Internal medicine; Oncology; Cyclophosphamide; Chemotherapy; Refractory (planetary science); Salvage therapy; Prednisone; CHOP; Autologous stem-cell transplantation","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002241557,0.0001821551,0.0003251642,0.0003049207,0.0003100327,0.0002597215,0.0003378236,0.0003632715,0.003961583],"category_scores_gemma":[0.0001815416,0.00004614732,0.0002617677,0.0002680657,0.000200213,0.0001769917,0.0001662436,0.0007097083,0.00105484],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001404091,"about_ca_system_score_gemma":0.0008051996,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01169506,"about_ca_topic_score_gemma":0.02899677,"domain_scores_codex":[0.9999274,0.00001317647,0.000002643061,0.000006006301,0.00002406357,0.00002667763],"domain_scores_gemma":[0.9999436,0.000006935352,0.000007136837,0.000004508428,0.00001124181,0.00002661367],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003648278,0.001522646,0.003442711,0.0005499033,0.0002045501,0.003685922,0.0001940738,0.001670385,0.03115266,0.003010413,0.06705559,0.883863],"study_design_scores_gemma":[0.01441991,0.0215555,0.08560919,0.0005322147,0.000472538,0.02482265,0.0003701466,0.01084647,0.02815623,0.00473971,0.8083688,0.0001066268],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.6749475,0.1622351,0.009782253,0.013225,0.002444444,0.000964988,0.0009816404,0.001637468,0.1337817],"genre_scores_gemma":[0.9499873,0.02617445,0.002777511,0.002986321,0.0004054478,0.0001626921,0.001077275,0.00005523624,0.0163738],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.01169506,"threshold_uncertainty_score":0.02325398,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01717987800143865,"score_gpt":0.2704167497535929,"score_spread":0.2532368717521542,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}