{"id":"W4384493020","doi":"10.1111/pde.15378","title":"Efficacy and safety of ritlecitinib in adolescents with alopecia areata: Results from the <scp>ALLEGRO</scp> phase 2b/3 randomized, double‐blind, placebo‐controlled trial","year":2023,"lang":"en","type":"article","venue":"Pediatric Dermatology","topic":"Hair Growth and Disorders","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Probity Medical Research; SKiN Health; Queen's University","funders":"Pfizer","keywords":"Medicine; Alopecia areata; Placebo; Adverse effect; Hair loss; Randomized controlled trial; Internal medicine; Scalp; Gastroenterology; Dermatology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001515295,0.0005461783,0.001678509,0.0001914015,0.0002191522,0.0005755095,0.0003472569,0.0007584044,0.002620299],"category_scores_gemma":[0.001259199,0.0002002638,0.002492495,0.000226454,0.0002500928,0.0003695705,0.0001662772,0.001185886,0.000280181],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004713675,"about_ca_system_score_gemma":0.0007733156,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006157787,"about_ca_topic_score_gemma":0.002513102,"domain_scores_codex":[0.999411,0.0003136116,0.000079729,0.00008060277,0.00006167099,0.00005340234],"domain_scores_gemma":[0.9990394,0.000277148,0.0003638813,0.00005440516,0.00008836052,0.0001768658],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9034568,0.002272064,0.01209307,0.003126968,0.00793273,0.0001510341,0.0001303351,0.0004478662,0.006858842,0.0001068462,0.00217111,0.06125233],"study_design_scores_gemma":[0.8468533,0.09297617,0.04312786,0.0004607975,0.009222768,0.0005201639,0.0001016731,0.0007314181,0.002132782,0.0001778708,0.003661184,0.00003394425],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.976232,0.01932339,0.0003171385,0.0003605312,0.0001362546,0.0009452078,0.00124004,0.00005528217,0.001390053],"genre_scores_gemma":[0.9925862,0.004169302,0.0005109354,0.0004665987,0.0001302251,0.0007472406,0.0009004021,0.00001113018,0.0004779431],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002620299,"threshold_uncertainty_score":0.008765817,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01954850968765241,"score_gpt":0.2870573750350667,"score_spread":0.2675088653474142,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}