{"id":"W4384493020","doi":"10.1111/pde.15378","title":"Efficacy and safety of ritlecitinib in adolescents with alopecia areata: Results from the <scp>ALLEGRO</scp> phase 2b/3 randomized, double‐blind, placebo‐controlled trial","year":2023,"lang":"en","type":"article","venue":"Pediatric Dermatology","topic":"Hair Growth and Disorders","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Probity Medical Research; SKiN Health; Queen's University","funders":"Pfizer","keywords":"Medicine; Alopecia areata; Placebo; Adverse effect; Hair loss; Randomized controlled trial; Internal medicine; Scalp; Gastroenterology; Dermatology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008705998,0.0003122311,0.001736425,0.0004161446,0.00009484142,0.0000191669,0.0002030701,0.0002551783,0.0000117901],"category_scores_gemma":[0.003204986,0.0001930519,0.0001796214,0.0008565082,0.0002682465,0.00007215337,0.00008623984,0.0004058497,0.00005645254],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001797684,"about_ca_system_score_gemma":0.0002883991,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002152473,"about_ca_topic_score_gemma":0.000216769,"domain_scores_codex":[0.996889,0.0004906604,0.001209968,0.0005004349,0.0003704985,0.0005394388],"domain_scores_gemma":[0.9950325,0.003885966,0.0003565844,0.0004178385,0.00009500321,0.0002120467],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.981834,0.0005929224,0.01184031,0.00007971508,0.0001625877,0.0002789471,0.001097879,0.00001314781,0.000003363145,0.00004795173,0.003738071,0.0003111359],"study_design_scores_gemma":[0.9934306,0.0002434379,0.003645382,0.00007412489,0.0007115764,0.00006871741,0.0005069255,0.0003020937,0.00001498909,0.00006724801,0.0008516237,0.00008328323],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877396,0.001566134,0.00007431457,0.00120656,0.0003037791,0.006029805,0.00007415707,0.00008687147,0.002918838],"genre_scores_gemma":[0.9968653,0.001642787,0.00004139421,0.000268717,0.0004707064,0.0003164007,0.000233356,0.00003260495,0.0001287227],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01159663,"threshold_uncertainty_score":0.7872427,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01954850968765241,"score_gpt":0.2870573750350667,"score_spread":0.2675088653474142,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}