{"id":"W4384499645","doi":"10.1080/2162402x.2023.2233403","title":"Longitudinal immune monitoring of patients with resectable esophageal adenocarcinoma treated with Neoadjuvant PD-L1 checkpoint inhibition","year":2023,"lang":"en","type":"article","venue":"OncoImmunology","topic":"Esophageal Cancer Research and Treatment","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Medicine; Peripheral blood mononuclear cell; CD8; Biomarker; Oncology; Immune system; Internal medicine; Neoadjuvant therapy; Flow cytometry; Gastroenterology; Cancer; Cancer research; Immunology; Breast cancer; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001642446,0.0002520717,0.0005683435,0.0003504113,0.0001298304,0.00001313202,0.00009718929,0.0001224388,0.0001283418],"category_scores_gemma":[0.00003674375,0.0001734289,0.00008018954,0.0008071432,0.0002582049,0.0001312589,0.00009396848,0.000344389,0.00008825721],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003566167,"about_ca_system_score_gemma":0.0002318596,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008932546,"about_ca_topic_score_gemma":0.00002925679,"domain_scores_codex":[0.9980532,0.00007582205,0.00035418,0.0004292115,0.0004737558,0.0006138517],"domain_scores_gemma":[0.9988236,0.00006526735,0.0001629743,0.0004951925,0.0003288508,0.0001240709],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.008172885,0.0004925909,0.984158,0.0001149163,0.000456104,0.001393215,0.0002096278,0.00001575105,0.002421146,0.00003257197,0.00002852475,0.002504632],"study_design_scores_gemma":[0.009171809,0.009760463,0.9272009,0.0002930725,0.000124966,0.00007157761,0.0001817657,0.00001261752,0.05302537,0.00001638989,0.00001768708,0.0001234351],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943706,0.004048048,0.00001163148,0.0001698079,0.00006258732,0.0006940589,0.0000320015,0.0001345113,0.0004767604],"genre_scores_gemma":[0.9979511,0.0001782998,0.000326266,0.000006027714,0.00006506124,0.0001487053,0.0003254176,0.00004922811,0.0009499093],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05695719,"threshold_uncertainty_score":0.7072225,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02181698149004652,"score_gpt":0.2832220520964986,"score_spread":0.2614050706064521,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}