{"id":"W4384522425","doi":"10.1001/jamaneurol.2023.2169","title":"Associations of Sex, Race, and Apolipoprotein E Alleles With Multiple Domains of Cognition Among Older Adults","year":2023,"lang":"en","type":"article","venue":"JAMA Neurology","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute on Aging; Canadian Institutes of Health Research; Avid Radiopharmaceuticals; Genentech; National Institutes of Health; IXICO; H. Lundbeck A/S; Servier; Eisai; Rush University; University of Washington; Pfizer; Biogen; BioClinica; Northern California Institute for Research and Education; Nancy and Buster Alvord Endowment; Siemens Medical Solutions USA; F. Hoffmann-La Roche; University of Pennsylvania; Vanderbilt University; U.S. Department of Defense; Eli Lilly and Company; Kaiser Permanente; University of Southern California; Vanderbilt Memory and Alzheimer's Center; Bristol-Myers Squibb; Novartis Pharmaceuticals Corporation; Alzheimer's Association; Alzheimer's Disease Neuroimaging Initiative; National Center for Advancing Translational Sciences; Meso Scale Diagnostics","keywords":"Apolipoprotein E; Cognition; Psychology; Gerontology; Demography; Medicine; Internal medicine; Disease; Psychiatry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000953758,0.0002308798,0.0002323461,0.000496969,0.000409083,0.0004042548,0.000271581,0.0002939115,0.001913437],"category_scores_gemma":[0.00227773,0.0001497654,0.0003771294,0.000560222,0.0002070787,0.000375971,0.0002767029,0.0002688576,0.0001929372],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001262662,"about_ca_system_score_gemma":0.000244411,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004231169,"about_ca_topic_score_gemma":0.01024123,"domain_scores_codex":[0.9995998,0.0001079813,0.00005584532,0.0001065844,0.00007629919,0.00005358876],"domain_scores_gemma":[0.9990447,0.0001586987,0.0005064652,0.00008994063,0.0001018104,0.0000982726],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00006571719,0.00001583099,0.9984181,0.000004273223,0.00005917778,0.00001903251,0.00004603068,0.000009771379,0.00009178272,0.00001187807,0.00004833695,0.001210039],"study_design_scores_gemma":[0.00000322296,0.00004317511,0.9994527,0.000005724206,0.00003670173,0.00007915282,0.00007857198,0.00008651157,0.00005083076,0.00004032665,0.0001214148,0.000001693026],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986547,0.0003771522,0.0001239515,0.00006314825,0.000008134438,0.00000507207,0.0003229881,0.000002791923,0.0004420353],"genre_scores_gemma":[0.999226,0.0001170377,0.0001238933,0.00003187528,0.00001109716,0.000007664366,0.0001986773,0.000001652953,0.0002821723],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004231169,"threshold_uncertainty_score":0.008413076,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01120249411631392,"score_gpt":0.273635744775752,"score_spread":0.2624332506594381,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}