{"id":"W4384523262","doi":"10.56367/oag-039-10859","title":"Understanding immune mechanisms to create novel treatments for primary biliary cholangitis","year":2023,"lang":"en","type":"article","venue":"Open Access Government","topic":"Liver Diseases and Immunity","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Primary biliary cirrhosis; Medicine; Gastroenterology; Jaundice; Nausea; Internal medicine; Obeticholic acid; Vomiting; Abdominal pain; Immune system; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001029114,0.0004445181,0.0005304191,0.0009426573,0.0003223428,0.001194761,0.0004577202,0.001337919,0.00794774],"category_scores_gemma":[0.0009403151,0.0001378227,0.0005777535,0.0002475662,0.0006219456,0.001388505,0.0007604937,0.003127312,0.001779034],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007193887,"about_ca_system_score_gemma":0.0007469324,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004208333,"about_ca_topic_score_gemma":0.001052295,"domain_scores_codex":[0.999622,0.0001163762,0.00002796423,0.0000312934,0.0001241765,0.00007809974],"domain_scores_gemma":[0.9995884,0.0001431537,0.00007538519,0.00001702969,0.00009974457,0.00007626646],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004586014,0.0006796136,0.002322991,0.003807789,0.0001860487,0.0009940331,0.0003207918,0.0007925674,0.02304834,0.03221687,0.1383042,0.7968683],"study_design_scores_gemma":[0.0002641108,0.0009928227,0.00347769,0.002517297,0.0001927546,0.002072497,0.0003737831,0.0005984681,0.007284575,0.01947652,0.9627079,0.00004170181],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.01305704,0.8173813,0.007354551,0.1218732,0.00895831,0.0001358883,0.0002392663,0.00028168,0.03071872],"genre_scores_gemma":[0.09874427,0.7970625,0.01238018,0.05400809,0.01598137,0.0002214474,0.000312184,0.00006284318,0.02122721],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.00794774,"threshold_uncertainty_score":0.02658784,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2511134022162392,"score_gpt":0.3997279189452498,"score_spread":0.1486145167290106,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}