{"id":"W4384561715","doi":"10.1186/s40635-023-00533-3","title":"Development and characterization of a fecal-induced peritonitis model of murine sepsis: results from a multi-laboratory study and iterative modification of experimental conditions","year":2023,"lang":"en","type":"article","venue":"Intensive Care Medicine Experimental","topic":"Sepsis Diagnosis and Treatment","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Ottawa Hospital; Health Sciences Centre; Thrombosis and Atherosclerosis Research Institute; Lawson Health Research Institute; Western University; University of Alberta; University of Calgary; McMaster University; University of Manitoba; Manitoba Health; Royal Alexandra Hospital","funders":"Ottawa Hospital Anesthesia Alternate Funds Association; Manitoba Medical Service Foundation; McMaster University; Canadian Institutes of Health Research; Royal Alexandra Hospital Foundation; University of Ottawa","keywords":"Sepsis; Medicine; Peritonitis; Feces; Antibiotics; Internal medicine; Gastroenterology; Microbiology; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003334049,0.001221382,0.001004795,0.0009461507,0.000549342,0.0008768957,0.0008774232,0.0008386511,0.0006866417],"category_scores_gemma":[0.001134562,0.0003426644,0.001122698,0.0004398446,0.0007496304,0.0006907771,0.0009161374,0.001955604,0.0004032858],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006504919,"about_ca_system_score_gemma":0.0007454814,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007555924,"about_ca_topic_score_gemma":0.001290584,"domain_scores_codex":[0.9977288,0.0005543705,0.0002941369,0.000460296,0.0006437984,0.000318675],"domain_scores_gemma":[0.9976133,0.0002530714,0.0006578347,0.0003805676,0.0006205629,0.000474597],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003623665,0.0008322853,0.001302144,0.00008915861,0.00002882084,0.00006074867,0.00009809618,0.0001696944,0.9951478,0.00005038196,0.00006882873,0.001789623],"study_design_scores_gemma":[0.0001306574,0.01329697,0.01829132,0.00003560335,0.0002074936,0.0005120283,0.0001511271,0.002220937,0.9630553,0.00008453759,0.001964041,0.0000500292],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.9500656,0.0009081878,0.04543016,0.000198062,0.00008092798,0.001268594,0.0009584327,0.0002879884,0.0008020899],"genre_scores_gemma":[0.884128,0.001252602,0.1055633,0.0002849585,0.00005474622,0.002849202,0.003719166,0.0001815916,0.001966515],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.003334049,"threshold_uncertainty_score":0.01763231,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1465623449562603,"score_gpt":0.3950869202397564,"score_spread":0.2485245752834961,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}