{"id":"W4384564952","doi":"10.1016/j.jpain.2023.07.009","title":"The Optimal Learning Cocktail for Placebo Analgesia: A Randomized Controlled Trial Comparing Individual and Combined Techniques","year":2023,"lang":"en","type":"article","venue":"Journal of Pain","topic":"Pain Management and Placebo Effect","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Universiteit Leiden; Arthritis Society; ReumaNederland; Dutch Arthritis Society","keywords":"Placebo; Observational study; Observational learning; Medicine; Extinction (optical mineralogy); Anxiety; Conditioning; Anesthesia; Classical conditioning; Placebo group; Randomized controlled trial; Physical therapy; Psychology; Audiology; Psychiatry; Surgery; Internal medicine; Alternative medicine; Experiential learning","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.08537207,0.0001491963,0.0009277143,0.0002566624,0.000461643,0.0002707786,0.0002860842,0.00005551082,0.000004003719],"category_scores_gemma":[0.0399787,0.00008766052,0.0003530949,0.0002382075,0.0001394711,0.0001190764,0.00006925186,0.0003390869,0.000001943224],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001801248,"about_ca_system_score_gemma":0.00003846746,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001181361,"about_ca_topic_score_gemma":0.000001443596,"domain_scores_codex":[0.9891291,0.009353649,0.0006793926,0.0001451483,0.0004067151,0.0002859991],"domain_scores_gemma":[0.93963,0.05949337,0.0006835917,0.00007705143,0.00005022577,0.00006575099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9854878,0.00002931772,0.0001340156,0.00002307133,0.0001586826,0.00002535796,0.0002198087,0.0003921937,0.002301365,0.0007329699,0.004905122,0.005590279],"study_design_scores_gemma":[0.8114582,0.000742557,0.00002131442,0.00006198459,0.0001809274,0.000006309019,0.0001919841,0.1822551,0.0008719387,0.0005633086,0.00353809,0.0001081724],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8691084,0.0003231435,0.1095528,0.004280028,0.0009991337,0.0132831,0.000003277252,0.0003104345,0.002139662],"genre_scores_gemma":[0.9976997,0.0003109584,0.0004147248,0.0001586249,0.0002557656,0.0002619287,0.000001458863,0.00001715394,0.0008797037],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.181863,"threshold_uncertainty_score":0.9681079,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03106105142709384,"score_gpt":0.2939227412824066,"score_spread":0.2628616898553128,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}