{"id":"W4384565542","doi":"10.1016/j.clml.2023.07.004","title":"Effect of the Presence of t(11;14) for Patients With AL Amyloidosis Treated With Bortezomib-Containing Regimens: Experience From the Amyloidosis Program of Calgary","year":2023,"lang":"en","type":"letter","venue":"Clinical Lymphoma Myeloma & Leukemia","topic":"Amyloidosis: Diagnosis, Treatment, Outcomes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Cancer Research; Foothills Medical Centre; University of Calgary","funders":"","keywords":"Bortezomib; AL amyloidosis; Amyloidosis; Immunoglobulin light chain; Amyloid (mycology); Medicine; Internal medicine; Melphalan; Oncology; Gastroenterology; Pathology; Immunology; Multiple myeloma; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001298388,0.0002040642,0.0005554077,0.0001976748,0.0007629091,0.0008383692,0.0004782077,0.001157499,0.001446193],"category_scores_gemma":[0.007272656,0.00009486277,0.0006534203,0.0005583623,0.0002410199,0.0004015222,0.0002796924,0.00136202,0.0002149314],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001667383,"about_ca_system_score_gemma":0.001327355,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01200336,"about_ca_topic_score_gemma":0.02029828,"domain_scores_codex":[0.9993338,0.0003646845,0.00005995381,0.00005922222,0.00009386438,0.00008852397],"domain_scores_gemma":[0.9940978,0.00313333,0.0006759129,0.0001246412,0.0003525669,0.001615719],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.03393764,0.004108571,0.6750693,0.0001767016,0.0008302078,0.008841517,0.0007109649,0.001797939,0.001549461,0.0006746376,0.04316776,0.2291353],"study_design_scores_gemma":[0.005474411,0.01727274,0.9433145,0.0001946818,0.001108162,0.007624643,0.0008404975,0.001760308,0.0008359841,0.00148418,0.02002893,0.00006107945],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9255021,0.006828976,0.0001656353,0.05071656,0.000650778,0.00006531086,0.0007640614,0.00002771091,0.01527868],"genre_scores_gemma":[0.9819655,0.002282074,0.0003080771,0.01221168,0.0006901004,0.00004194264,0.0004993584,0.00001430416,0.001986922],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01200336,"threshold_uncertainty_score":0.02386701,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01389741909341276,"score_gpt":0.2946554675333239,"score_spread":0.2807580484399112,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}