{"id":"W4384655665","doi":"10.5281/zenodo.8162181","title":"GENOME-WIDE ASSOCIATION STUDIES (GWAS) HAVE REVOLUTIONIZED OUR VIEW OF HUMAN HEALTH AND DISEASE GENETICS AND OFFERED NOVEL GENE THERAPY TARGETS","year":2023,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Nutrition, Genetics, and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Genome-wide association study; Disease; Biology; Genetic association; Genetics; Computational biology; Human genome; Genome; Genetic enhancement; Gene; Medicine; Single-nucleotide polymorphism; Genotype; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.016454,0.0009035467,0.00192711,0.004655154,0.001777618,0.005092072,0.001806156,0.003777523,0.02091475],"category_scores_gemma":[0.0297875,0.0007395243,0.002152702,0.004650826,0.004830095,0.004986207,0.003971183,0.006508375,0.004013561],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002472309,"about_ca_system_score_gemma":0.004153143,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01021319,"about_ca_topic_score_gemma":0.01541862,"domain_scores_codex":[0.9926373,0.003931649,0.0004594576,0.001391067,0.001264902,0.0003156704],"domain_scores_gemma":[0.9560493,0.03122755,0.003643665,0.003986527,0.003708637,0.001384464],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.001273096,0.0008290274,0.1878609,0.006255479,0.002947786,0.00152828,0.00251032,0.002284104,0.01188172,0.1210541,0.08751167,0.5740636],"study_design_scores_gemma":[0.0003007991,0.0007754259,0.1892792,0.006860053,0.001898079,0.004051042,0.004889967,0.002753332,0.005120943,0.3675981,0.4159974,0.0004756336],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"review","genre_scores_codex":[0.08045936,0.2875555,0.1208233,0.4068339,0.008172754,0.0003243492,0.0128222,0.001390061,0.08161853],"genre_scores_gemma":[0.3828898,0.3166727,0.146829,0.1147508,0.01298534,0.0005301527,0.006029819,0.0005716409,0.01874072],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.02091475,"threshold_uncertainty_score":0.08701807,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05188385768532087,"score_gpt":0.299266888535532,"score_spread":0.2473830308502111,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}