{"id":"W4384662375","doi":"10.1073/pnas.2213768120","title":"Multigenerational adversity impacts on human gut microbiome composition and socioemotional functioning in early childhood","year":2023,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Mental Health; Medical Research Council; National Institute for Health and Care Research; Singapore Institute for Clinical Sciences; National University Health System; National Research Foundation; National Medical Research Council; National Research Foundation Singapore","keywords":"Socioemotional selectivity theory; Microbiome; Anxiety; Gut microbiome; Mental health; Psychopathology; Biology; Psychology; Developmental psychology; Clinical psychology; Psychiatry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002256899,0.0002202938,0.0001835562,0.000343945,0.0003509836,0.0004933376,0.00009591218,0.0002107608,0.001258658],"category_scores_gemma":[0.0006213973,0.0001581896,0.000205474,0.0002990182,0.0003048413,0.0002206427,0.0007383716,0.0003058964,0.0001186978],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002930332,"about_ca_system_score_gemma":0.0002519416,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006061316,"about_ca_topic_score_gemma":0.01220108,"domain_scores_codex":[0.9998454,0.00005283768,0.000006644274,0.0000350794,0.0000217949,0.00003824067],"domain_scores_gemma":[0.9997717,0.00003647926,0.00008329855,0.00003372744,0.00002185123,0.00005297405],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002240723,0.00003898585,0.9627934,0.00004058026,0.000112259,0.0003048606,0.0009776986,0.0001392484,0.02520646,0.000157948,0.0001225115,0.009882018],"study_design_scores_gemma":[5.224169e-7,0.00002992393,0.9988964,0.000003184975,0.000008538322,0.000101653,0.0002082961,0.00004561388,0.0005420607,0.00003857476,0.0001234841,0.000001847605],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991465,0.0002554416,0.0001141428,0.00002915587,0.000001612998,0.000002575403,0.0001567801,0.000002111732,0.000291556],"genre_scores_gemma":[0.9991948,0.0002592771,0.0001629098,0.00001639434,0.000001240488,0.000004210792,0.0001160962,0.00000157392,0.0002435384],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006061316,"threshold_uncertainty_score":0.01205206,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03277376809073516,"score_gpt":0.3098701109035048,"score_spread":0.2770963428127696,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}