{"id":"W4384662972","doi":"10.2217/imt-2023-0012","title":"Mirikizumab for the Treatment of Moderate to Severe Ulcerative Colitis","year":2023,"lang":"en","type":"review","venue":"Immunotherapy","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; University of Calgary","funders":"","keywords":"Ulcerative colitis; Tofacitinib; Medicine; Colitis; Drug; Inflammation; Internal medicine; Immunology; Pharmacology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003475227,0.0006619832,0.0009950267,0.00162144,0.0002174214,0.0006232386,0.0006956381,0.0007247675,0.003722013],"category_scores_gemma":[0.0004093934,0.000176441,0.0004812039,0.001166427,0.0002769507,0.0006455,0.0004627445,0.001736076,0.002304756],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003506668,"about_ca_system_score_gemma":0.00049639,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005952278,"about_ca_topic_score_gemma":0.001488659,"domain_scores_codex":[0.9998878,0.00001976805,0.00001611757,0.00001960554,0.000042933,0.00001376468],"domain_scores_gemma":[0.9998819,0.0000503854,0.00002270342,0.000003565873,0.00002573903,0.00001575072],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001310463,0.00006648313,0.00009691595,0.008725191,0.00009124647,0.0002160388,0.00002975324,0.0002053183,0.001236225,0.001360529,0.02784734,0.959994],"study_design_scores_gemma":[0.00007336975,0.000131746,0.0007359786,0.002915228,0.000161593,0.002086175,0.00002661187,0.00009019033,0.0004588377,0.001092166,0.9922131,0.00001499284],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001609326,0.9982734,0.00009142045,0.0001723572,0.0001951395,0.000005572154,0.00001535525,0.000008958602,0.001076804],"genre_scores_gemma":[0.001219983,0.9972625,0.0001600877,0.0002566256,0.0001606654,0.000008411027,0.00004328278,0.000002558134,0.0008859034],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003722013,"threshold_uncertainty_score":0.01245135,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04020959227294852,"score_gpt":0.3431351967940178,"score_spread":0.3029256045210693,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}