{"id":"W4384662972","doi":"10.2217/imt-2023-0012","title":"Mirikizumab for the Treatment of Moderate to Severe Ulcerative Colitis","year":2023,"lang":"en","type":"review","venue":"Immunotherapy","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; University of Calgary","funders":"","keywords":"Ulcerative colitis; Tofacitinib; Medicine; Colitis; Drug; Inflammation; Internal medicine; Immunology; Pharmacology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001033372,0.0003443929,0.0006279857,0.00004632179,0.0001096407,0.00002941293,0.0002820677,0.000200533,0.00001756505],"category_scores_gemma":[0.00001619416,0.0002212866,0.0006550954,0.00008250658,0.00005290238,0.000001444284,0.00002314815,0.00003907846,0.00003770217],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007745982,"about_ca_system_score_gemma":0.0003604437,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001680101,"about_ca_topic_score_gemma":0.00007004617,"domain_scores_codex":[0.9988416,0.0001154872,0.0003738166,0.0003388299,0.00009179873,0.0002384988],"domain_scores_gemma":[0.998917,0.00008137722,0.0001824536,0.0006651232,0.0001073172,0.00004672677],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002191314,0.000108267,2.978383e-7,0.001321297,0.001929011,0.0000110215,0.0002637217,0.00005179624,0.00004330588,0.0001916855,0.001744004,0.9921443],"study_design_scores_gemma":[0.0007929775,0.0005025813,0.00005622431,0.0004745334,0.000186508,0.000005514928,0.00001881517,0.00001195142,0.0001296478,0.00002926669,0.997546,0.000246008],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006316854,0.9942319,0.0002640866,0.00003003845,0.0002543445,0.003369186,0.001133907,0.00001708522,0.00006770326],"genre_scores_gemma":[0.00002229886,0.9919767,0.0001290363,0.00008861451,0.0002542643,0.002414058,0.0003401781,0.000111321,0.004663562],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.995802,"threshold_uncertainty_score":0.9023804,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04020959227294852,"score_gpt":0.3431351967940178,"score_spread":0.3029256045210693,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}