{"id":"W4384701084","doi":"10.1016/j.euo.2023.06.006","title":"Prognostic Significance of Grade Discrepancy Between Primary Tumor and Venous Thrombus in Nonmetastatic Clear-cell Renal Cell Carcinoma: Analysis of the REMEMBER Registry and Implications for Adjuvant Therapy","year":2023,"lang":"en","type":"article","venue":"European Urology Oncology","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Shanghai Education Development Foundation; Changhai Hospital of Shanghai; Shanghai Municipal Health Bureau; Shanghai Municipal Education Commission; National Natural Science Foundation of China","keywords":"Medicine; Renal cell carcinoma; Internal medicine; Hazard ratio; Clear cell renal cell carcinoma; Oncology; Nephrectomy; Proportional hazards model; Adjuvant therapy; Cancer; Urology; Confidence interval; Kidney","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005544457,0.0001812072,0.0008163123,0.0002630064,0.00006532062,0.000003298775,0.0001607365,0.00006389054,0.000005688259],"category_scores_gemma":[0.0000962498,0.0001209427,0.0001417311,0.0006667824,0.0005162988,0.00002058465,0.0001210818,0.0002079575,0.000002209586],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006448237,"about_ca_system_score_gemma":0.0001655647,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005360465,"about_ca_topic_score_gemma":0.00003929751,"domain_scores_codex":[0.9980006,0.0005835725,0.0005589416,0.0004555175,0.0001023227,0.0002990223],"domain_scores_gemma":[0.997991,0.0009290905,0.0004214845,0.0005057305,0.00006791378,0.00008480198],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004669609,0.0006621343,0.9338214,0.0002180014,0.0003475124,0.000136747,0.0009677372,0.00005055524,0.06076857,0.00003010745,0.0001661635,0.002364159],"study_design_scores_gemma":[0.002469663,0.003507176,0.9889078,0.000009190818,0.001865295,0.00004517302,0.00008545998,0.00007283833,0.002317134,0.0001127903,0.0005154293,0.00009211068],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943155,0.001327237,0.00005293501,0.00155085,0.00003204971,0.001171367,0.0001015139,0.00001874046,0.00142982],"genre_scores_gemma":[0.9985456,0.0001838579,0.0006820646,0.0001804168,0.0000337007,0.00006055317,0.0001038364,0.00003605755,0.0001738696],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05845143,"threshold_uncertainty_score":0.4931901,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03875623152503214,"score_gpt":0.2903480757409217,"score_spread":0.2515918442158895,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}