{"id":"W4384818778","doi":"10.1111/tan.15157","title":"Genome‐wide association studies of response and side effects to the <scp>BNT162b2</scp> vaccine in Italian healthcare workers: Increased antibody levels and side effects in carriers of the <i>HLA‐A*03:01</i> allele","year":2023,"lang":"en","type":"article","venue":"HLA","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Surgical Specialties (Canada)","funders":"","keywords":"Genome-wide association study; Medicine; Genotyping; Vaccination; SNP; Immunology; Genotype; Single-nucleotide polymorphism; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001049571,0.0003864602,0.0003164819,0.0004901563,0.0002797761,0.0004184199,0.0002596088,0.0004975795,0.001677236],"category_scores_gemma":[0.001814169,0.0001955016,0.0009096568,0.0009260438,0.0003018516,0.0001218638,0.0002999124,0.0003723706,0.0001954135],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002160005,"about_ca_system_score_gemma":0.0002081552,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004369801,"about_ca_topic_score_gemma":0.004899648,"domain_scores_codex":[0.9993455,0.0002571422,0.00005518525,0.000193609,0.00006522919,0.00008333439],"domain_scores_gemma":[0.9984084,0.0004687854,0.0007056239,0.0002077518,0.00007642135,0.0001330285],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009457492,0.00004804658,0.9905112,0.00003624896,0.0005568568,0.0002059294,0.000141013,0.0001169292,0.004831018,0.00002380881,0.0001097546,0.002473363],"study_design_scores_gemma":[0.00001262325,0.00008402693,0.9993113,0.000002902563,0.0001176926,0.0001107528,0.0000271705,0.0000860154,0.0001272369,0.00001216599,0.000106027,0.000002106484],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992231,0.0002689604,0.00009909894,0.00003736997,0.000004248303,0.00000438812,0.0001707967,0.000002953065,0.0001890771],"genre_scores_gemma":[0.9993387,0.0001251866,0.0001150214,0.00003353148,0.00001037278,0.000006792604,0.0002377941,0.000002977129,0.0001295752],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004369801,"threshold_uncertainty_score":0.008688748,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03120534672626033,"score_gpt":0.3588403292357522,"score_spread":0.3276349825094918,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}