{"id":"W4384923460","doi":"10.1158/1078-0432.ccr-23-0757","title":"Molecular Residual Disease in Breast Cancer: Detection and Therapeutic Interception","year":2023,"lang":"en","type":"review","venue":"Clinical Cancer Research","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Medicine; Breast cancer; Oncology; Disease; Clinical trial; Internal medicine; Minimal residual disease; Cancer; Immunotherapy; Leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007169812,0.0007968788,0.001481112,0.002402243,0.000236136,0.0009559018,0.001036259,0.001135165,0.003124834],"category_scores_gemma":[0.0009110833,0.0002974924,0.0005743612,0.001940877,0.0005266372,0.001338755,0.0006798938,0.00211655,0.002271001],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007154346,"about_ca_system_score_gemma":0.0009659933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008273291,"about_ca_topic_score_gemma":0.001556911,"domain_scores_codex":[0.999752,0.00005363144,0.00003103023,0.00003920214,0.0001013519,0.00002287432],"domain_scores_gemma":[0.9996299,0.0002083018,0.00003993136,0.0000121986,0.00008277047,0.00002691817],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007863007,0.00006161875,0.000125653,0.01788421,0.00007536064,0.0001289832,0.00004175075,0.0003209142,0.0010582,0.003594768,0.02916809,0.9474618],"study_design_scores_gemma":[0.00002164769,0.0001068048,0.0006130998,0.005104838,0.00009565074,0.001145338,0.00004139946,0.00007580826,0.0003158512,0.002253861,0.9902087,0.00001694917],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004949572,0.9989397,0.00006730718,0.0002163978,0.0001374612,0.000003640747,0.00001294058,0.000004916431,0.0005681422],"genre_scores_gemma":[0.000300366,0.9990251,0.00009489631,0.0001656599,0.0001041479,0.00000518377,0.00002065048,0.000001116337,0.000282817],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003124834,"threshold_uncertainty_score":0.01045358,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2059661286484782,"score_gpt":0.5311124960904527,"score_spread":0.3251463674419746,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}