{"id":"W4384929976","doi":"10.3390/cimb45070381","title":"EMT Features in Claudin-Low versus Claudin-Non-Suppressed Breast Cancers and the Role of Epigenetic Modifications","year":2023,"lang":"en","type":"review","venue":"Current Issues in Molecular Biology","topic":"Barrier Structure and Function Studies","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"NOSM University; Essar Steel Algoma (Canada); Sault Area Hospital","funders":"","keywords":"Claudin; Epigenetics; Cancer research; Methyltransferase; Breast cancer; DNA methylation; Biology; Epithelial–mesenchymal transition; Phenotype; Methylation; CDH1; Internal medicine; Tight junction; Medicine; Cancer; Gene; Cell; Gene expression; Metastasis; Genetics; Cadherin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002024898,0.0003755877,0.001238232,0.0003419583,0.00009071944,0.00002165143,0.0005191292,0.0002741085,0.000008622217],"category_scores_gemma":[0.0004105846,0.000255142,0.0002056193,0.0008065904,0.0008974922,0.00002175773,0.0002903065,0.0005960183,0.00001038935],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007462491,"about_ca_system_score_gemma":0.0001336438,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001364087,"about_ca_topic_score_gemma":0.0001050586,"domain_scores_codex":[0.9975392,0.0006640733,0.0005935695,0.0007092973,0.0001371925,0.0003566911],"domain_scores_gemma":[0.9985027,0.0005872516,0.0003140604,0.0005096951,0.00003836378,0.0000479574],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002350065,0.00006885771,0.00008280652,0.003631398,0.0001811943,0.00001568583,0.001210564,0.00007794602,0.001766824,0.02252746,0.0004903685,0.9697119],"study_design_scores_gemma":[0.002474401,0.000117995,0.0002506602,0.003471733,0.0004657643,0.00003405258,0.0002678375,0.00007349314,0.001530104,0.008347332,0.9822164,0.000750281],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002398794,0.996713,0.00006212207,0.0001038911,0.001483511,0.0008540828,0.0002081025,0.00002354951,0.0003118525],"genre_scores_gemma":[0.01189697,0.9874685,0.00002081784,0.00002076056,0.00008908001,0.0003983984,0.00004293821,0.00003218215,0.00003036294],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.981726,"threshold_uncertainty_score":0.9999901,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04553434231109093,"score_gpt":0.3818859769569307,"score_spread":0.3363516346458398,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}