{"id":"W4384937287","doi":"10.1016/j.envint.2023.108103","title":"The epigenetic hallmark of early-life α-hexabromocyclododecane exposure: From cerebellar 6-mA levels to locomotor performance in adulthood","year":2023,"lang":"en","type":"article","venue":"Environment International","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Ministère de l'Education Nationale, de l'Enseignement Superieur et de la Recherche; Agence Nationale de la Recherche","keywords":"Epigenetics; Offspring; Biology; DNA methylation; Serotonergic; Methylation; GABAergic; Methylated DNA immunoprecipitation; Endocrinology; Internal medicine; Genetics; Gene expression; Gene; Serotonin; Medicine; Pregnancy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006416804,0.0002478872,0.0001984436,0.00028756,0.0001617966,0.0002556874,0.0001630757,0.0002359155,0.001321002],"category_scores_gemma":[0.0001106934,0.0001295689,0.0001863649,0.0001695798,0.0001980455,0.000156268,0.0002041358,0.0004261587,0.0001662115],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000355429,"about_ca_system_score_gemma":0.0002105562,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002648761,"about_ca_topic_score_gemma":0.005582199,"domain_scores_codex":[0.9999052,0.000005031937,0.00000502773,0.00004392256,0.00002337462,0.00001742608],"domain_scores_gemma":[0.9999095,0.000006646272,0.00003144212,0.000009189954,0.00002354309,0.00001957872],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001405364,0.00001054861,0.002596105,0.00002780439,0.00001228509,0.00004966085,0.00003248292,0.00002150851,0.9941084,0.00004417063,0.00003248506,0.002923985],"study_design_scores_gemma":[0.000007201332,0.0003873286,0.1548236,0.00001622434,0.00005870378,0.000319252,0.0001181417,0.0002181114,0.8404456,0.0001451682,0.003448563,0.00001212261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900497,0.00273448,0.003725305,0.0001121441,0.00004425521,0.00002032359,0.001731973,0.0001155427,0.001466343],"genre_scores_gemma":[0.9905606,0.001593826,0.001795046,0.00008123787,0.000007487306,0.00004255385,0.00124069,0.00002879409,0.004649842],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002648761,"threshold_uncertainty_score":0.005266726,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01345169878353978,"score_gpt":0.237582972909935,"score_spread":0.2241312741263953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}