{"id":"W4384937514","doi":"10.1016/j.ajoc.2023.101902","title":"Acanthamoeba-associated retinitis successfully treated with intravitreal and systemic antimicrobials","year":2023,"lang":"en","type":"article","venue":"American Journal of Ophthalmology Case Reports","topic":"Legionella and Acanthamoeba research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Genentech; National Institutes of Health; Oregon Health and Science University; National Eye Institute; Roche; Gilead Sciences; Research to Prevent Blindness","keywords":"Medicine; Voriconazole; Acanthamoeba; Retinitis; Fluconazole; Acanthamoeba keratitis; Vancomycin; Dermatology; Keratitis; Ophthalmology; Immunology; Microbiology; Antifungal; Staphylococcus aureus; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003551521,0.001219958,0.0009774095,0.001602142,0.002445359,0.001264504,0.0009625023,0.002916045,0.001179612],"category_scores_gemma":[0.001989939,0.0007168773,0.001236637,0.0009156225,0.0013225,0.0009767863,0.001259129,0.001878495,0.0005192878],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001281608,"about_ca_system_score_gemma":0.001160301,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003717559,"about_ca_topic_score_gemma":0.005646841,"domain_scores_codex":[0.9990789,0.0001196247,0.00008382924,0.0001798855,0.0001925864,0.0003451632],"domain_scores_gemma":[0.9989896,0.0002051747,0.0002426789,0.0001351979,0.00006905697,0.0003581866],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00004577525,0.00005438533,0.004977956,0.00002568761,0.00001112152,0.9911314,0.0001050035,0.00004908987,0.001165546,0.0001271905,0.00009513507,0.002211648],"study_design_scores_gemma":[0.00001675612,0.00005866222,0.003883728,0.00001814543,0.00002974371,0.9938779,0.00008291956,0.0003933838,0.0008585511,0.0000830028,0.0006894104,0.00000775042],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9582261,0.01233989,0.005173741,0.00246509,0.0004528025,0.0002571168,0.0001204521,0.0002995494,0.02066528],"genre_scores_gemma":[0.9947849,0.00137879,0.001265992,0.0006844149,0.0003633607,0.00002611501,0.00005425061,0.00001669524,0.001425596],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003717559,"threshold_uncertainty_score":0.009298742,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0122223359014919,"score_gpt":0.2817598490895512,"score_spread":0.2695375131880592,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}