{"id":"W4384938353","doi":"10.1016/j.immuni.2023.06.022","title":"The gut protist Tritrichomonas arnold restrains virus-mediated loss of oral tolerance by modulating dietary antigen-presenting dendritic cells","year":2023,"lang":"en","type":"article","venue":"Immunity","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; Population Health Research Institute","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; University of Pittsburgh; Medical Center, University of Pittsburgh; Heinz Endowments; National Institutes of Health; Nature; Children's Hospital of Pittsburgh; Tsinghua University; McMaster University; Marshallplan-Jubiläumsstiftung; Canadian Institutes of Health Research; China Scholarship Council; National Cancer Institute; Melanoma Research Alliance","keywords":"Biology; Virology; Antigen; Protist; Tritrichomonas foetus; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008864707,0.0001443501,0.0001486629,0.000166955,0.0002050184,0.0002778889,0.0001300276,0.0003357681,0.001392981],"category_scores_gemma":[0.0001640621,0.00007031446,0.000112319,0.0001249807,0.0001713598,0.0001907568,0.0003276121,0.0004732731,0.0002328069],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001639961,"about_ca_system_score_gemma":0.000207645,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007226222,"about_ca_topic_score_gemma":0.001129298,"domain_scores_codex":[0.9999261,0.0000132752,0.000003569943,0.00001418032,0.00001866666,0.00002412567],"domain_scores_gemma":[0.9999044,0.000009555653,0.00003626777,0.000009306014,0.000009268522,0.00003125923],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003628384,0.00002817053,0.001170738,0.00003541281,0.000006924956,0.00009536769,0.00002787608,0.0000392965,0.992801,0.0001029094,0.0001013607,0.005228106],"study_design_scores_gemma":[0.0001341717,0.00313964,0.04906087,0.00004785636,0.00007868598,0.001286171,0.0008571381,0.001594641,0.9218876,0.0004780484,0.02140803,0.00002717366],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952354,0.001791345,0.0007038881,0.0003463481,0.00008587436,0.00001154674,0.0001371664,0.00003865261,0.001649787],"genre_scores_gemma":[0.9970681,0.0009224084,0.0006366746,0.00006347137,0.0000201815,0.000006636551,0.00009287758,0.000008454467,0.001181187],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001392981,"threshold_uncertainty_score":0.00466001,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0471644676855028,"score_gpt":0.3374317117214496,"score_spread":0.2902672440359468,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}