{"id":"W4384938644","doi":"10.1016/j.neurobiolaging.2023.07.021","title":"Biomarkers of Alzheimer’s disease in Black and/or African American Alzheimer’s Disease Neuroimaging Initiative (ADNI) participants","year":2023,"lang":"en","type":"article","venue":"Neurobiology of Aging","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Genentech; IXICO; H. Lundbeck A/S; Servier; Eisai; Northern California Institute for Research and Education; University of Southern California; Biogen; BioClinica; U.S. Department of Defense; Meso Scale Diagnostics; Alzheimer's Disease Neuroimaging Initiative; Novartis Pharmaceuticals Corporation; Pfizer; Eli Lilly and Company; Bristol-Myers Squibb; National Institute on Aging; Alzheimer's Association; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Alzheimer's Disease Neuroimaging Initiative; Dementia; Biomarker; Neuroimaging; Alzheimer's disease; Oncology; Psychology; White matter; Cerebrospinal fluid; Internal medicine; Hyperintensity; Population; Magnetic resonance imaging; Apolipoprotein E; Medicine; Disease; Neuroscience; Biology; Radiology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009521251,0.0005938805,0.0004312519,0.001334528,0.0009899475,0.0008238484,0.0003940484,0.0006529002,0.001449465],"category_scores_gemma":[0.002106871,0.0003361601,0.000426305,0.001145212,0.0001769688,0.0008791211,0.0006122875,0.0005788156,0.000224211],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003682558,"about_ca_system_score_gemma":0.000434103,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01125027,"about_ca_topic_score_gemma":0.017875,"domain_scores_codex":[0.999697,0.00007165869,0.00003437159,0.00006716794,0.00005745425,0.00007247517],"domain_scores_gemma":[0.9994745,0.00004610013,0.0002505084,0.00002770817,0.0001127677,0.00008843931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006308465,0.0001217785,0.9939373,0.00003807606,0.0002028227,0.0001037915,0.0002194677,0.0000219969,0.0007890238,0.00009458823,0.0007940326,0.00304641],"study_design_scores_gemma":[0.00003735134,0.0001656875,0.9968599,0.00003941692,0.0001841967,0.0003101253,0.0005359341,0.0001137757,0.0002732997,0.0002493308,0.001219658,0.00001139693],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952615,0.00118178,0.0001341387,0.0001941647,0.00004722563,0.00002619189,0.001669639,0.000005343784,0.001480049],"genre_scores_gemma":[0.9959116,0.0005972543,0.0004779051,0.0001988362,0.00005466447,0.00008413805,0.00151136,0.000004752174,0.001159591],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01125027,"threshold_uncertainty_score":0.02236956,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08768592163160996,"score_gpt":0.3710676029475,"score_spread":0.28338168131589,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}