{"id":"W4384942580","doi":"10.3791/64770","title":"A Human Cerebral Organoid Model of Neural Cell Transplantation","year":2023,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Fonds de Recherche du Québec - Santé","keywords":"Organoid; Transplantation; Induced pluripotent stem cell; Xenotransplantation; Context (archaeology); Neural stem cell; Progenitor cell; Biology; Neuroscience; Stem cell; Embryonic stem cell; Cell biology; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002365465,0.0001080833,0.0001902773,0.0001477076,0.00004917905,0.00001313481,0.0002282013,0.00008360796,0.00003138247],"category_scores_gemma":[0.00001168732,0.00009709819,0.0001399629,0.0001303718,0.00003934809,0.00001013771,0.00005258152,0.00008835677,0.000007552168],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001564646,"about_ca_system_score_gemma":0.00006440903,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004571871,"about_ca_topic_score_gemma":6.486135e-7,"domain_scores_codex":[0.9987878,0.00008541343,0.0004143358,0.0001316345,0.0003760347,0.0002047555],"domain_scores_gemma":[0.9993991,0.000005631339,0.000243084,0.0001229039,0.0001358283,0.0000934202],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002418596,0.0001386302,0.0005210845,0.00004951956,0.00004283283,0.00001494052,0.0002971975,0.001361856,0.9961997,0.00001302478,0.001081832,0.00003753317],"study_design_scores_gemma":[0.002118484,0.000429929,0.0004963435,0.00001832937,0.00001685006,0.00001759865,0.0001271788,0.003302524,0.9932995,0.00002388297,0.00005968988,0.00008969869],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983431,0.0001974837,0.0009159901,0.00003252059,0.00008640427,0.00009531854,0.00001315572,0.000005542357,0.0003105496],"genre_scores_gemma":[0.9984127,0.0001249448,0.0004731691,0.0000320756,0.00007567424,0.000003293913,0.00003933078,0.00002285657,0.0008159581],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002900199,"threshold_uncertainty_score":0.3959549,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03952250406074016,"score_gpt":0.4092958935383797,"score_spread":0.3697733894776395,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}