{"id":"W4384965809","doi":"","title":"Highly sensitive determination of PIK3CA exon 9 and 20 hotspot mutations in breast tumors","year":2012,"lang":"en","type":"preprint","venue":"HAL (Le Centre pour la Communication Scientifique Directe)","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre d'expertise et de recherche en infrastructures urbaines","funders":"","keywords":"Hotspot (geology); Exon; Cancer research; Computer science; Genetics; Medicine; Biology; Gene; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008308934,0.0003177123,0.0004414477,0.001850928,0.0002173077,0.0005773767,0.0002917865,0.0007238463,0.001882688],"category_scores_gemma":[0.001320331,0.0003682012,0.0002063489,0.0006119489,0.0002391418,0.0002055695,0.0003930182,0.0004713226,0.0009573924],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003504106,"about_ca_system_score_gemma":0.0001876753,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007144987,"about_ca_topic_score_gemma":0.001350425,"domain_scores_codex":[0.9990625,0.0001835469,0.00006903651,0.000250645,0.0003240591,0.0001101714],"domain_scores_gemma":[0.9994259,0.0002884112,0.00006421714,0.00005602251,0.0001096814,0.0000557213],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002541089,0.0001427507,0.08405203,0.0001664773,0.000123082,0.001209248,0.0002012056,0.0004955572,0.8555537,0.0002337362,0.001349112,0.05393199],"study_design_scores_gemma":[0.0001378981,0.0007379556,0.4406491,0.00004800778,0.0003249105,0.01267628,0.0001723294,0.004805519,0.5307637,0.0007839088,0.008841833,0.00005859591],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9774185,0.006296362,0.00764036,0.0002680373,0.0001181536,0.00008727854,0.001538672,0.0003262392,0.006306467],"genre_scores_gemma":[0.9835414,0.001166181,0.01009986,0.0001668226,0.00005616355,0.00005160673,0.001274544,0.00003506653,0.003608344],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001882688,"threshold_uncertainty_score":0.006298244,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01261205276941322,"score_gpt":0.2534977641502165,"score_spread":0.2408857113808033,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}