{"id":"W4385064689","doi":"10.1007/s12010-023-04604-9","title":"A Multi-epitope Vaccine Candidate Against Bolivian Hemorrhagic fever Caused by Machupo Virus","year":2023,"lang":"en","type":"article","venue":"Applied Biochemistry and Biotechnology","topic":"vaccines and immunoinformatics approaches","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"","keywords":"Epitope; Virology; Immune system; Virus; Antigen; Peptide vaccine; Glycoprotein; Biology; Immunology; Molecular biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001729218,0.0003826228,0.0003235955,0.00009222619,0.0002025473,0.00004895968,0.0004004452,0.000839026,0.00001593081],"category_scores_gemma":[0.00003807378,0.0003485189,0.00007706165,0.0003705742,0.0001345769,0.000005896292,0.0004948486,0.0002929795,0.00005473888],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001920214,"about_ca_system_score_gemma":0.00004583554,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002540431,"about_ca_topic_score_gemma":0.00001508747,"domain_scores_codex":[0.9982998,0.00001157441,0.0003769979,0.000614967,0.0001087282,0.0005879034],"domain_scores_gemma":[0.9990302,0.000009339336,0.0001476666,0.0006554431,0.00003243791,0.0001249396],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000481703,0.00006802336,0.0001692642,0.00007798202,0.00008790834,0.00000598974,0.00002421518,0.000003665036,0.9804738,0.00002426307,0.009376129,0.009640588],"study_design_scores_gemma":[0.001420722,0.00006961229,0.0002581359,0.00001006763,0.00002611683,0.00003031847,0.0002996882,0.0004791342,0.9596838,0.00003074091,0.03724362,0.0004480099],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963785,0.001305778,0.0002446891,0.001028174,0.00007575855,0.0002793213,0.0001605186,0.000191118,0.0003361249],"genre_scores_gemma":[0.9923263,0.003474415,0.0007458594,0.0005849769,0.00009843024,0.00007675247,0.001652952,0.00004296962,0.0009972987],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02786749,"threshold_uncertainty_score":0.9998967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006724744714718268,"score_gpt":0.2121537333164198,"score_spread":0.2054289886017015,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}