{"id":"W4385068933","doi":"10.3390/molecules28145549","title":"Biological Activity and Structural Diversity of Steroids Containing Aromatic Rings, Phosphate Groups, or Halogen Atoms","year":2023,"lang":"en","type":"review","venue":"Molecules","topic":"Marine Sponges and Natural Products","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lethbridge College","funders":"","keywords":"Marine invertebrates; Biological activity; Terpenoid; Quantitative structure–activity relationship; Computational biology; Chemistry; In vitro; Biology; Stereochemistry; Biochemistry; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002480882,0.0003717893,0.0009355824,0.00006475015,0.0001517169,0.00002121596,0.0003140654,0.0003641108,0.00001057375],"category_scores_gemma":[0.0002118457,0.0002466614,0.0002176845,0.0001425758,0.0001611725,0.000004455921,0.001576069,0.0002454671,0.000003573194],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001634096,"about_ca_system_score_gemma":0.0000533885,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001012247,"about_ca_topic_score_gemma":0.00004343724,"domain_scores_codex":[0.9985073,0.0002027703,0.0002991699,0.0005823753,0.0001293726,0.000278962],"domain_scores_gemma":[0.9991846,0.00005794653,0.0003067948,0.0003329476,0.00003318514,0.00008452756],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003016132,0.00003751081,0.0009846003,0.009822955,0.0009445621,0.00008855463,0.00006760298,8.874115e-7,0.002672856,0.0001034437,0.0001515442,0.9848239],"study_design_scores_gemma":[0.006773538,0.01208834,0.04596851,0.01871644,0.005722849,0.001354639,0.0004406527,0.0002454582,0.02699891,0.00275427,0.869297,0.009639348],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.3566278,0.6427858,0.00001255716,0.000008640052,0.0001098676,0.000336271,0.00007048374,0.00002064772,0.00002793415],"genre_scores_gemma":[0.1200884,0.8791168,0.0001384391,0.00001669826,0.000102106,0.00001089133,0.0002459468,0.00003097463,0.0002497641],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9751845,"threshold_uncertainty_score":0.9999986,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05210935120552396,"score_gpt":0.3062665316772492,"score_spread":0.2541571804717253,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}