{"id":"W4385077305","doi":"10.3168/jdsc.2022-0333","title":"Effect of pH and lipopolysaccharide on tight junction regulators and inflammatory markers in intestinal cells as an experimental model of weaning transition in dairy calves","year":2023,"lang":"en","type":"article","venue":"JDS Communications","topic":"Barrier Structure and Function Studies","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of Food and Agriculture; University of Alberta","keywords":"Lipopolysaccharide; Weaning; Transition (genetics); Inflammatory response; Immunology; Biology; Chemistry; Cell biology; Animal science; Inflammation; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002623899,0.00008814217,0.0001487197,0.0002447034,0.0001054596,0.00000865949,0.0001183037,0.00004282842,0.000002388155],"category_scores_gemma":[0.0000808875,0.0000831703,0.00002048361,0.0002364404,0.0002562858,0.0001715142,0.00009056204,0.0001460221,6.513279e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002289669,"about_ca_system_score_gemma":0.00001559768,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008301025,"about_ca_topic_score_gemma":0.00005826894,"domain_scores_codex":[0.9991938,0.0002323006,0.000226373,0.0001604315,0.0001021031,0.00008502158],"domain_scores_gemma":[0.9992075,0.0003412165,0.00007560552,0.0003325078,0.00001274006,0.00003045033],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001795444,0.0000382871,0.001986648,0.0000348967,0.00000329436,6.024392e-7,0.004361362,0.000768534,0.9886792,0.002205464,0.00001405995,0.001728075],"study_design_scores_gemma":[0.0008962313,0.0005495243,0.01918643,0.0001619813,0.0000170821,0.000005739809,0.002652782,0.08006544,0.8955241,0.0007904596,0.00001305807,0.0001371558],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990982,0.0000645328,0.00003064297,0.00009859079,0.00004582417,0.0001671264,0.000005195701,0.0000289064,0.000460951],"genre_scores_gemma":[0.9996103,0.0001541327,0.0001379452,0.00003379908,0.000004766111,0.00003250517,0.000003605002,0.000007909855,0.00001505482],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09315512,"threshold_uncertainty_score":0.3391587,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02744532879476396,"score_gpt":0.2924147828662138,"score_spread":0.2649694540714498,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}