{"id":"W4385173573","doi":"10.1016/j.esmoop.2023.101613","title":"Incidence of interstitial lung disease and cardiotoxicity with trastuzumab deruxtecan in breast cancer patients: a systematic review and single-arm meta-analysis","year":2023,"lang":"en","type":"review","venue":"ESMO Open","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"Daiichi Sankyo Europe; Daiichi-Sankyo","keywords":"Medicine; Internal medicine; Breast cancer; Incidence (geometry); Asymptomatic; Cardiotoxicity; Oncology; Gastroenterology; Lung cancer; Cancer; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008566621,0.001870083,0.01440588,0.005615258,0.000484226,0.002349006,0.001560532,0.001414552,0.002726184],"category_scores_gemma":[0.01844614,0.001136035,0.03018571,0.006381675,0.0005824152,0.00118138,0.001171336,0.001096038,0.0002234],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002227024,"about_ca_system_score_gemma":0.002744502,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006010298,"about_ca_topic_score_gemma":0.0152982,"domain_scores_codex":[0.994327,0.002116994,0.002067981,0.0006226832,0.0006694782,0.000195971],"domain_scores_gemma":[0.9887045,0.007293914,0.002449152,0.0003562234,0.001034089,0.0001620867],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.00186259,0.00003223138,0.005322513,0.47104,0.5096733,0.0001383016,0.0000766872,0.0004311221,0.0002782354,0.0001051283,0.0006645509,0.0103754],"study_design_scores_gemma":[0.0005322311,0.0001908322,0.005084621,0.02990268,0.9621166,0.0001212291,0.0000359508,0.0001572372,0.0001230723,0.0001301436,0.001582219,0.00002318519],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.007767315,0.9901793,0.0003809838,0.0001500979,0.0001014834,0.0003246406,0.0007812643,0.00002258627,0.0002923885],"genre_scores_gemma":[0.2213894,0.7729459,0.001706654,0.0009212208,0.0002084721,0.00124124,0.001142929,0.00003466169,0.0004095123],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01440588,"threshold_uncertainty_score":0.04530513,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1500703787125109,"score_gpt":0.4438841884306995,"score_spread":0.2938138097181886,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}