{"id":"W4385201495","doi":"10.21203/rs.3.rs-3084236/v1","title":"The role of specific isoforms of CaV2 and the common C-terminal of CaV2 in calcium channel function in sensory neurons of Aplysia","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"Neurobiology and Insect Physiology Research","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Aplysia; Habituation; Neuroscience; Gene isoform; Biology; Alternative splicing; Stimulus (psychology); Sensory neuron; Sensory system; Cell biology; Chemistry; Biochemistry; Psychology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001031808,0.0002032765,0.0002106214,0.0002826526,0.0001843726,0.0003449066,0.0002119446,0.0003474541,0.0007199387],"category_scores_gemma":[0.0002543207,0.0001630177,0.0002557476,0.0001749407,0.0002831598,0.0002555645,0.000257622,0.0004554687,0.000216749],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003746466,"about_ca_system_score_gemma":0.0001755098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007519076,"about_ca_topic_score_gemma":0.0009147292,"domain_scores_codex":[0.9998986,0.0000103308,0.00001743728,0.00003062172,0.00002183111,0.00002126879],"domain_scores_gemma":[0.9998099,0.00002566497,0.0000581617,0.0000217687,0.00002227106,0.00006224702],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001034524,0.000006221095,0.0005708382,0.00001199487,0.000003446438,0.0000714441,0.00001338239,0.0000287876,0.9989206,0.00005213506,0.00001191092,0.0002058906],"study_design_scores_gemma":[0.00008048069,0.0003162335,0.1996993,0.00002444499,0.00005797254,0.002464435,0.0003040956,0.003162926,0.7909051,0.0003357352,0.002626223,0.00002288672],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987134,0.000249283,0.0005214267,0.00003166453,0.00000748241,0.000003552994,0.0001789357,0.00001156894,0.0002825811],"genre_scores_gemma":[0.9976879,0.0001290533,0.0007218471,0.00004040518,0.000005295686,0.00001322881,0.0005784745,0.00001315782,0.0008105712],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007519076,"threshold_uncertainty_score":0.00271827,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1125504932794662,"score_gpt":0.3806401845620589,"score_spread":0.2680896912825927,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}