{"id":"W4385209656","doi":"10.1038/s41557-023-01259-1","title":"Total synthesis of strychnan alkaloids","year":2023,"lang":"en","type":"article","venue":"Nature Chemistry","topic":"Lichen and fungal ecology","field":"Agricultural and Biological Sciences","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université du Québec à Montréal","funders":"","keywords":"Chemistry; Total synthesis; Stereochemistry; Combinatorial chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00008368334,0.00007375525,0.0001212408,0.000003165576,0.00004351383,0.000006975716,0.0001682973,0.0003740597,0.0009650627],"category_scores_gemma":[0.0001731471,0.00002806799,0.00007269585,0.0003019166,0.00004061888,0.00002223808,0.00005961836,0.0002327083,0.00004307152],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009124506,"about_ca_system_score_gemma":0.000005941255,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001044778,"about_ca_topic_score_gemma":0.00000648214,"domain_scores_codex":[0.9994513,0.000008618598,0.000103176,0.0001596249,0.0001094357,0.0001677854],"domain_scores_gemma":[0.9996292,0.0001974329,0.00004261795,0.00004597333,0.00003358764,0.00005117287],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000007319497,0.00002165426,0.003131627,0.00001797091,0.000009078806,0.000004409489,0.000007827057,5.717176e-7,0.9812999,0.00003115863,0.003595129,0.01187341],"study_design_scores_gemma":[0.00004457806,0.00002084021,0.1274028,0.00001148345,0.000008092675,0.000008076303,0.0001384277,0.00001719423,0.864338,0.0001318406,0.007769656,0.0001090308],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9854063,0.00008786059,2.114577e-8,0.0008062889,0.00008862358,0.00002880281,0.00006192009,0.00008210031,0.0134381],"genre_scores_gemma":[0.9978289,0.00001495211,0.0000109394,0.00006650313,0.0002364917,0.000007229123,0.0000473356,5.677272e-7,0.001787099],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1242712,"threshold_uncertainty_score":0.9999482,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00520863527531865,"score_gpt":0.2045292343896272,"score_spread":0.1993205991143086,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}