{"id":"W4385224046","doi":"10.1136/ard-2023-224123","title":"The 2022 EULAR/ACR points to consider at the early stages of diagnosis and management of suspected haemophagocytic lymphohistiocytosis/macrophage activation syndrome (HLH/MAS)","year":2023,"lang":"en","type":"review","venue":"Annals of the Rheumatic Diseases","topic":"Autoimmune and Inflammatory Disorders Research","field":"Medicine","cited_by":136,"is_retracted":false,"has_abstract":false,"ca_institutions":"Pediatric Oncology Group; Lawson Health Research Institute; Western University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of General Medical Sciences; Swedish Orphan Biovitrum; National Institutes of Health; Incyte; Adaptive Biotechnologies; Regeneron Pharmaceuticals; Alexion Pharmaceuticals; National Institute of Allergy and Infectious Diseases; Pfizer; Eli Lilly and Company","keywords":"Medicine; Macrophage activation syndrome; Delphi method; Intensive care medicine; Disease; Multidisciplinary approach; Rheumatology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001036646,0.0007012198,0.001829242,0.00313662,0.0002895918,0.00110502,0.0009008767,0.001491441,0.006298133],"category_scores_gemma":[0.002428442,0.0002608016,0.00110753,0.001778271,0.0003540627,0.00106627,0.0008336834,0.001835706,0.002749952],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006997692,"about_ca_system_score_gemma":0.00226487,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002188389,"about_ca_topic_score_gemma":0.005035576,"domain_scores_codex":[0.9995965,0.00008065895,0.0001064302,0.00004330773,0.00013253,0.0000405743],"domain_scores_gemma":[0.9990265,0.0004144104,0.0001914924,0.00002077341,0.0002840684,0.00006274301],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001412696,0.00004139794,0.0003907796,0.03132898,0.0002300681,0.0004301161,0.00003738719,0.0001474145,0.0005654756,0.001529448,0.1020153,0.8631422],"study_design_scores_gemma":[0.00009197682,0.00009999436,0.002064544,0.04346009,0.0007591292,0.002523976,0.00006840837,0.00006221433,0.00023696,0.001214776,0.9493896,0.00002831855],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007735628,0.9960178,0.0001151959,0.001345738,0.0007231588,0.00001660799,0.000100706,0.00001291993,0.001590575],"genre_scores_gemma":[0.0008213032,0.9951798,0.0004930861,0.002041698,0.0005163278,0.00001759963,0.0001753922,0.000002793087,0.0007519718],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006298133,"threshold_uncertainty_score":0.02106935,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08957347039567064,"score_gpt":0.3815346864440365,"score_spread":0.2919612160483658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}