{"id":"W4385235057","doi":"10.1016/j.ijbiomac.2023.125962","title":"Genome-scale CRISPR screen identifies TRIM2 and SLC35A1 associated with porcine epidemic diarrhoea virus infection","year":2023,"lang":"en","type":"article","venue":"International Journal of Biological Macromolecules","topic":"Animal Virus Infections Studies","field":"Agricultural and Biological Sciences","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ministry of Agriculture","funders":"","keywords":"Porcine epidemic diarrhea virus; Biology; Virology; Vero cell; Gene; Viral replication; CRISPR; Virus; Microbiology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002013825,0.0003296143,0.0004555006,0.0002626372,0.0002853759,0.0004242619,0.0003430458,0.0005794918,0.002094399],"category_scores_gemma":[0.0003035893,0.0001769299,0.0004869651,0.0001790131,0.0002148281,0.0001216866,0.0004380165,0.0006298615,0.0004830695],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002541603,"about_ca_system_score_gemma":0.000244573,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001182811,"about_ca_topic_score_gemma":0.002599407,"domain_scores_codex":[0.9998086,0.00002112097,0.00001527843,0.00005604086,0.00005821534,0.00004087723],"domain_scores_gemma":[0.9998823,0.00003642711,0.00002782226,0.00001434413,0.00001093268,0.00002807807],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001866403,0.00003868027,0.002087872,0.0001525899,0.0000414934,0.0009621127,0.00003449984,0.0003235548,0.9912394,0.0002125961,0.0006232543,0.004097362],"study_design_scores_gemma":[0.0001470345,0.0007606594,0.07770036,0.00009157763,0.000618958,0.008122525,0.0003838001,0.01614318,0.8602989,0.000576084,0.03507429,0.00008262326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9818789,0.002037123,0.008458328,0.0003944609,0.0002108996,0.00006236036,0.002476116,0.0005732967,0.003908343],"genre_scores_gemma":[0.9903312,0.0005314765,0.003751522,0.0003207831,0.00001376733,0.00003319978,0.002035036,0.00007401641,0.002909038],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002094399,"threshold_uncertainty_score":0.007006407,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03281934400468339,"score_gpt":0.2713241185154388,"score_spread":0.2385047745107554,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}