{"id":"W4385235327","doi":"10.1021/jacs.3c02103","title":"Mechanistic Investigations of Phenoxyimine–Cobalt(II)-Catalyzed C(sp<sup>2</sup>)–C(sp<sup>3</sup>) Suzuki–Miyaura Cross-Coupling","year":2023,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Catalytic Cross-Coupling Reactions","field":"Chemistry","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Bristol-Myers Squibb","keywords":"Chemistry; Transmetalation; Cobalt; Methoxide; Bromide; Electron paramagnetic resonance; Nuclear magnetic resonance spectroscopy; Catalysis; Aryl; Fluorine-19 NMR; Catalytic cycle; Sodium methoxide; Alkyl; Physical chemistry; Inorganic chemistry; Stereochemistry; Organic chemistry; Nuclear magnetic resonance","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008871136,0.000572813,0.001183067,0.0001037177,0.0007362387,0.0001923025,0.001669763,0.0002929209,0.0002569436],"category_scores_gemma":[0.002227123,0.000478773,0.0017941,0.002083588,0.002275372,0.0003231163,0.0008070253,0.001669035,0.00004846761],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008487437,"about_ca_system_score_gemma":0.0006524479,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002834763,"about_ca_topic_score_gemma":0.000001998361,"domain_scores_codex":[0.995346,0.000005558984,0.001761095,0.0006030018,0.001368218,0.0009161023],"domain_scores_gemma":[0.9942728,0.001093817,0.002203387,0.001187891,0.000753005,0.0004890506],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008618009,0.0002773275,0.003428447,0.0001861007,0.00056707,0.000009786391,0.002265315,0.0276641,0.9586537,0.00008926466,0.006526389,0.0002462843],"study_design_scores_gemma":[0.001631392,0.00006072385,0.0005992405,0.0003603497,0.0006452178,0.0002541346,0.005309378,0.1091985,0.8780482,0.001973164,0.001248486,0.0006712142],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972683,0.00009986104,0.0001410186,0.001602327,0.0001666409,0.0001573509,0.0002607254,0.0001893395,0.0001144043],"genre_scores_gemma":[0.996954,0.0001068096,0.0009083041,0.000265046,0.0009416659,0.00002193382,0.00009536013,0.0001280795,0.0005788293],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08153434,"threshold_uncertainty_score":0.9997664,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01967268848722348,"score_gpt":0.2890235554066482,"score_spread":0.2693508669194247,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}