{"id":"W4385271314","doi":"10.1053/j.gastro.2023.07.015","title":"Germline Determinants of Esophageal Adenocarcinoma","year":2023,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Esophageal Cancer Research and Treatment","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cambridge Memorial Hospital; Grand River Hospital","funders":"Cleveland Clinic; Massachusetts Institute of Technology; National Institute of Diabetes and Digestive and Kidney Diseases; American College of Gastroenterology; Massachusetts General Hospital; Elsa U. Pardee Foundation","keywords":"Hiatal hernia; Adenocarcinoma; Esophageal adenocarcinoma; Esophagus; Medicine; Obesity; Internal medicine; Germline; Cancer; Oncology; Gastroenterology; Gene; Biology; Genetics; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004006063,0.0003234855,0.0006046472,0.001458168,0.0003976816,0.0007455436,0.0006144477,0.0006693715,0.01138879],"category_scores_gemma":[0.004711783,0.0002814485,0.0008316701,0.003639201,0.0002253624,0.0004693501,0.0008340655,0.0005958981,0.001331378],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003180508,"about_ca_system_score_gemma":0.0004232944,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01417059,"about_ca_topic_score_gemma":0.02085003,"domain_scores_codex":[0.999167,0.0001021853,0.0001494487,0.0003641623,0.0001091121,0.0001080908],"domain_scores_gemma":[0.9984078,0.0004162262,0.0006065616,0.0002138978,0.0002060263,0.0001496101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008665987,0.00002973238,0.9393705,0.001523116,0.0008442682,0.0005782066,0.0001953852,0.0005345588,0.0007491524,0.0006382547,0.03597888,0.01869145],"study_design_scores_gemma":[0.00007264937,0.00005776193,0.9787201,0.0005357383,0.0004058655,0.001953185,0.0001561674,0.0004087983,0.0002221301,0.0007754001,0.01667226,0.00001992751],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"dataset","genre_gemma":"empirical","genre_scores_codex":[0.4343877,0.01613156,0.0007656805,0.001215119,0.0001141999,0.00009722001,0.5388908,0.0001400418,0.008257669],"genre_scores_gemma":[0.7944714,0.00502269,0.001078476,0.0004074978,0.00009107945,0.0001602666,0.196787,0.0000939829,0.001887594],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01417059,"threshold_uncertainty_score":0.03809935,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02785971750420214,"score_gpt":0.3294216466633685,"score_spread":0.3015619291591664,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}