{"id":"W4385276976","doi":"10.1142/s2529732523400035","title":"Exosomes: From “Dust” to Design in Proteome Medicine","year":2023,"lang":"en","type":"article","venue":"Molecular Frontiers Journal","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Microvesicles; Proteome; Immune system; Proteomics; Saliva; Cell biology; Biology; Medicine; Computational biology; microRNA; Physiology; Bioinformatics; Immunology; Internal medicine; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006843005,0.0002325209,0.0002537708,0.0003271899,0.00008627296,0.00004601789,0.0005019103,0.0001675069,0.00005813506],"category_scores_gemma":[0.0004219078,0.0002214576,0.0001155187,0.0004925362,0.00009015553,0.00000817572,0.0001475855,0.000277339,0.00007893951],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006281868,"about_ca_system_score_gemma":0.0001310049,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001438073,"about_ca_topic_score_gemma":0.000004315681,"domain_scores_codex":[0.9980142,0.000285452,0.000395464,0.0004301931,0.0003748853,0.0004998222],"domain_scores_gemma":[0.9989539,0.00001165916,0.000103622,0.0004483698,0.00007736406,0.0004050351],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001756756,0.00004180509,0.002409243,0.000005834341,0.00008272412,0.001034469,0.0001764643,0.002210238,0.9086666,0.000007259703,0.08227401,0.00291564],"study_design_scores_gemma":[0.006064912,0.001491668,0.02003213,0.000340088,0.0001472066,0.0002209313,0.001705875,0.00201191,0.8710796,0.01204347,0.08352441,0.001337786],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6705384,0.003523878,0.3227102,0.001913792,0.0006070783,0.0004358642,0.00001079034,0.00003000063,0.0002299428],"genre_scores_gemma":[0.9571322,0.0003640246,0.03860829,0.001619847,0.0007750881,0.00008699274,0.0001201884,0.0001138098,0.001179615],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2865937,"threshold_uncertainty_score":0.9030778,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01494325003055068,"score_gpt":0.2646741987987905,"score_spread":0.2497309487682398,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}