{"id":"W4385283736","doi":"10.33393/dti.2012.1373","title":"Resveratrol Targeting of Carcinogen-Induced Brain Endothelial Cell Inflammation Biomarkers MMP-9 and COX-2 is Sirt1-Independent","year":2012,"lang":"en","type":"article","venue":"Drug Target Insights","topic":"Circular RNAs in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Resveratrol; Medicine; Inflammation; Matrix metalloproteinase; Bioinformatics; Carcinogen; Cancer research; Pharmacology; Neuroscience; Internal medicine; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000161658,0.0003604957,0.0002852592,0.000230821,0.0001568819,0.0003514909,0.0002246628,0.0003426998,0.003908625],"category_scores_gemma":[0.0001511594,0.0002173545,0.0005329707,0.00008062501,0.0003071744,0.000320531,0.0002078068,0.0008024337,0.0009073543],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002503512,"about_ca_system_score_gemma":0.0002629829,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004574179,"about_ca_topic_score_gemma":0.001410914,"domain_scores_codex":[0.9998354,0.00002545538,0.000009162582,0.00004257822,0.00005176175,0.00003568989],"domain_scores_gemma":[0.9998846,0.00001603265,0.00003011557,0.00002273971,0.00002354688,0.00002283346],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003368355,0.00004685164,0.0001624525,0.00006498617,0.00001930534,0.00004174923,0.00001280999,0.00004231232,0.9961303,0.0004312635,0.0001342251,0.002576793],"study_design_scores_gemma":[0.00005158023,0.0006668033,0.008047427,0.00001325542,0.00006449804,0.0002258006,0.00005090938,0.0006711393,0.9838972,0.0002786038,0.006024865,0.000007895704],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9610984,0.009488196,0.01478767,0.001284621,0.0003859119,0.00008032237,0.0009614049,0.0005324121,0.01138111],"genre_scores_gemma":[0.9848038,0.002047312,0.001665337,0.0002171695,0.00004530275,0.00002789497,0.0006554819,0.00004276847,0.01049493],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003908625,"threshold_uncertainty_score":0.01307571,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007731154081757723,"score_gpt":0.2262672031747568,"score_spread":0.218536049092999,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}