{"id":"W4385297552","doi":"10.1016/s2352-3026(23)00174-6","title":"Momelotinib versus danazol in symptomatic patients with anaemia and myelofibrosis previously treated with a JAK inhibitor (MOMENTUM): an updated analysis of an international, double-blind, randomised phase 3 study","year":2023,"lang":"en","type":"article","venue":"The Lancet Haematology","topic":"Myeloproliferative Neoplasms: Diagnosis and Treatment","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Myelofibrosis; Internal medicine; Danazol; Clinical endpoint; Ruxolitinib; Anemia; Post-hoc analysis; Randomized controlled trial; Intention-to-treat analysis; Adverse effect; Placebo; Gastroenterology; Surgery; Bone marrow; Endometriosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003587566,0.000294099,0.001668658,0.0006743823,0.00007893373,0.00003340013,0.0001853753,0.0000753467,0.0000735849],"category_scores_gemma":[0.00003734184,0.0001639693,0.00005667389,0.001564685,0.0001431413,0.0001699143,0.00005302883,0.0001347899,0.000004785885],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008269447,"about_ca_system_score_gemma":0.00006381726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002334277,"about_ca_topic_score_gemma":0.001398555,"domain_scores_codex":[0.9979658,0.000286492,0.0005372072,0.0004938186,0.0003683977,0.0003483118],"domain_scores_gemma":[0.9985387,0.0002403467,0.0003026187,0.0005894593,0.000187431,0.0001413868],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1522421,0.003554035,0.8361516,0.00004896504,0.004350688,0.0002167758,0.002761737,0.0001183533,0.00003673295,0.00006263991,0.00004160276,0.0004147319],"study_design_scores_gemma":[0.4475587,0.008377044,0.5340375,0.0001064241,0.004238862,0.00001969769,0.001270721,0.003232156,0.0009332219,0.000004539862,0.00001302896,0.0002080562],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996031,0.00001902653,0.000003098358,0.0003859303,0.00004154422,0.003276509,0.00006554041,0.00008824688,0.0000890565],"genre_scores_gemma":[0.9975232,0.00004245679,0.00009680721,0.00004910385,0.00002633109,0.000722989,0.001493554,0.00002927123,0.00001621813],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3021141,"threshold_uncertainty_score":0.6686475,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04147677945176609,"score_gpt":0.3467970079764283,"score_spread":0.3053202285246622,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}