{"id":"W4385297552","doi":"10.1016/s2352-3026(23)00174-6","title":"Momelotinib versus danazol in symptomatic patients with anaemia and myelofibrosis previously treated with a JAK inhibitor (MOMENTUM): an updated analysis of an international, double-blind, randomised phase 3 study","year":2023,"lang":"en","type":"article","venue":"The Lancet Haematology","topic":"Myeloproliferative Neoplasms: Diagnosis and Treatment","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Myelofibrosis; Internal medicine; Danazol; Clinical endpoint; Ruxolitinib; Anemia; Post-hoc analysis; Randomized controlled trial; Intention-to-treat analysis; Adverse effect; Placebo; Gastroenterology; Surgery; Bone marrow; Endometriosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002510003,0.001065984,0.003412993,0.0005296256,0.0002797433,0.001339443,0.0006241484,0.001140424,0.003460546],"category_scores_gemma":[0.003437152,0.0005135461,0.003503718,0.0006439007,0.0007219067,0.001344071,0.0004030187,0.002443261,0.0004472924],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007072668,"about_ca_system_score_gemma":0.0007266166,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007974922,"about_ca_topic_score_gemma":0.002875898,"domain_scores_codex":[0.9989541,0.000613644,0.0001014751,0.0001324654,0.00009176327,0.0001064968],"domain_scores_gemma":[0.9981468,0.0008850525,0.0005261774,0.0001214917,0.00009716642,0.0002233024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9419554,0.0008118718,0.001703274,0.00212509,0.007288032,0.0000644557,0.00007494582,0.0004850248,0.002326712,0.0001613335,0.001035199,0.04196852],"study_design_scores_gemma":[0.9476719,0.03197264,0.008829189,0.0002574875,0.008104309,0.0001336704,0.00006472255,0.0004663298,0.0004022486,0.0003439791,0.00170297,0.00005039262],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9329638,0.05653471,0.00118131,0.0014866,0.0009842048,0.001065706,0.001909604,0.0001947158,0.003679291],"genre_scores_gemma":[0.9818076,0.01176678,0.001222178,0.001504931,0.0004309386,0.0005117983,0.00124482,0.0000338151,0.001477193],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003460546,"threshold_uncertainty_score":0.01327431,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04147677945176609,"score_gpt":0.3467970079764283,"score_spread":0.3053202285246622,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}