{"id":"W4385300647","doi":"10.1016/j.cjca.2023.07.025","title":"The Role of Endoplasmic Reticulum Stress in Calcific Aortic Valve Disease","year":2023,"lang":"en","type":"review","venue":"Canadian Journal of Cardiology","topic":"Cardiac Valve Diseases and Treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Key Technology Research and Development Program of Shandong; Natural Science Foundation of Shandong Province","keywords":"Medicine; Calcification; Endoplasmic reticulum; Aortic valve; Stenosis; Bicuspid aortic valve; Unfolded protein response; Aortic valve stenosis; Internal medicine; Calcinosis; Cardiology; Pathology; Cell biology; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008093956,0.0008173851,0.002280909,0.002193732,0.0003277596,0.001391388,0.0008980861,0.001464173,0.003363109],"category_scores_gemma":[0.001171687,0.0002817734,0.0006749163,0.002203729,0.000499366,0.0009360826,0.0008044898,0.001955965,0.001109035],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007428901,"about_ca_system_score_gemma":0.002093786,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003774504,"about_ca_topic_score_gemma":0.00823371,"domain_scores_codex":[0.9997762,0.00003550337,0.00004111039,0.00003558819,0.00008713284,0.00002444238],"domain_scores_gemma":[0.9994081,0.0002812406,0.00008805591,0.00001057426,0.0001653888,0.00004669025],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000194546,0.0000775973,0.0003392957,0.03135132,0.0002792995,0.0002615076,0.0000540809,0.0002934749,0.0008740852,0.002203595,0.03447393,0.9295973],"study_design_scores_gemma":[0.0001252314,0.0001773553,0.002764838,0.01457902,0.0008443688,0.001293736,0.0001259622,0.000202738,0.0003314609,0.002407527,0.9770973,0.00005046404],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003411061,0.9994776,0.00002323086,0.0001538171,0.0001103126,0.000001355915,0.00000718038,0.000001847845,0.000190718],"genre_scores_gemma":[0.0003100047,0.9992501,0.00005062918,0.0001152994,0.0001457957,0.000001608923,0.00001007417,3.479812e-7,0.0001160209],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003774504,"threshold_uncertainty_score":0.01125067,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02454620411248922,"score_gpt":0.3418807471920705,"score_spread":0.3173345430795813,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}