{"id":"W4385319503","doi":"10.3390/md21080422","title":"Generation of Bioactive Peptides from Porphyridium sp. and Assessment of Their Potential for Use in the Prevention of Hypertension, Inflammation and Pain","year":2023,"lang":"en","type":"article","venue":"Marine Drugs","topic":"Protein Hydrolysis and Bioactive Peptides","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Vlaamse Instelling voor Technologisch Onderzoek","keywords":"Hydrolysate; Cyclooxygenase; Inflammation; Pharmacology; In silico; Enzyme; In vivo; Valdecoxib; Functional food; Chemistry; Carrageenan; IC50; Biochemistry; In vitro; Medicine; Biology; Food science; Immunology; Biotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001888868,0.0003721221,0.0002628496,0.0002503781,0.0001175329,0.0002446288,0.0001455432,0.0002946502,0.0006328147],"category_scores_gemma":[0.000204364,0.0001420469,0.0003604445,0.0002562472,0.0001196259,0.0002841046,0.0002146281,0.0007194648,0.0002111833],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001159464,"about_ca_system_score_gemma":0.0001452916,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001581755,"about_ca_topic_score_gemma":0.0002345147,"domain_scores_codex":[0.9999295,0.000008938703,0.000005423583,0.00001559801,0.00002601223,0.00001461006],"domain_scores_gemma":[0.9999026,0.00001939534,0.00004212407,0.00000730703,0.00001147871,0.00001721994],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009721841,0.00003448781,0.0001292267,0.0001458381,0.000009086964,0.0001394979,0.00001336478,0.0002911191,0.9955295,0.00004702072,0.00002518744,0.003538373],"study_design_scores_gemma":[0.0000474425,0.001309525,0.003117877,0.00003739495,0.00004838851,0.0006380164,0.00004307307,0.001044259,0.9894132,0.0001064689,0.00417971,0.00001467118],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9823406,0.005578688,0.009557149,0.0001557397,0.0000545383,0.0001492317,0.0006217277,0.00005245057,0.001489833],"genre_scores_gemma":[0.9755886,0.003575331,0.01814253,0.0000975646,0.00002671728,0.00008809874,0.000761384,0.0000318198,0.001687985],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006328147,"threshold_uncertainty_score":0.002116978,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03097066285299918,"score_gpt":0.2628871573513816,"score_spread":0.2319164944983824,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}