{"id":"W4385330523","doi":"10.1161/circinterventions.123.012997","title":"EXACT Trial: Results of the Phase 1 Dose-Escalation Study","year":2023,"lang":"en","type":"article","venue":"Circulation Cardiovascular Interventions","topic":"Cardiac Imaging and Diagnostics","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"De-escalation; Phase (matter); Medicine; Physics; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015421,0.0001192008,0.0004023141,0.0002307195,0.0001323576,0.00002687309,0.00008920999,0.00005927879,0.00002033038],"category_scores_gemma":[0.001808277,0.00009646007,0.003138367,0.001016367,0.00005816718,0.00007742194,0.00006423015,0.0001447928,0.0000613321],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006954863,"about_ca_system_score_gemma":0.00006073046,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007208231,"about_ca_topic_score_gemma":0.000005136472,"domain_scores_codex":[0.9979811,0.0003114072,0.000646265,0.0002772532,0.0006328479,0.0001511241],"domain_scores_gemma":[0.9983194,0.0001556223,0.0001561096,0.00102762,0.000279141,0.00006204431],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02331301,0.02707976,0.4252766,0.002673079,0.04209056,0.0003704549,0.009622671,0.1666419,0.003374026,0.001253014,0.05466279,0.2436422],"study_design_scores_gemma":[0.08316838,0.000332444,0.908226,0.0003361101,0.002601467,0.00002289195,0.0005221346,0.001415694,0.0001752181,0.00008492876,0.00299161,0.0001231722],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892505,0.0006626947,0.003909651,0.0003456342,0.00134604,0.002331917,0.00006929617,0.0002077725,0.001876526],"genre_scores_gemma":[0.9991207,0.00001295792,0.00002430404,0.00001420531,0.0002242416,0.00009563872,0.0001797766,0.00002331507,0.0003049359],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4829494,"threshold_uncertainty_score":0.3933527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08415818595471825,"score_gpt":0.3770272431910696,"score_spread":0.2928690572363514,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}