{"id":"W4385341089","doi":"10.21203/rs.3.rs-2944243/v3","title":"YAP1 controls the N-cadherin-mediated tumor-stroma interaction in melanoma progression","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Institute of Genetics; Cincinnati Children's Hospital Medical Center; National Institutes of Health; University of Texas Southwestern Medical Center; Georgia Clinical and Translational Science Alliance; University of Cincinnati","keywords":"Cadherin; Stroma; YAP1; Melanoma; Cancer research; Tumor progression; Medicine; Pathology; Biology; Internal medicine; Cancer; Genetics; Immunohistochemistry; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000180197,0.0003598248,0.0002571074,0.0003319397,0.000346178,0.0007135988,0.0002598176,0.0004566083,0.003482458],"category_scores_gemma":[0.0002593652,0.0002646453,0.0002319607,0.0001710705,0.0002811953,0.000511645,0.0004224174,0.00062007,0.000918884],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005861575,"about_ca_system_score_gemma":0.0002900652,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009973894,"about_ca_topic_score_gemma":0.001267243,"domain_scores_codex":[0.9998517,0.00001541562,0.000005390778,0.00004059496,0.00003421005,0.00005271863],"domain_scores_gemma":[0.9998673,0.00001589211,0.00004010722,0.0000135954,0.00001925245,0.00004383164],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003136889,0.00002334879,0.001089589,0.00005447255,0.000009846369,0.0001376955,0.00003313245,0.0003911781,0.9922059,0.001522907,0.0004578446,0.003760381],"study_design_scores_gemma":[0.00005458781,0.0001377454,0.04097288,0.0000149438,0.00003470209,0.0004437914,0.0001160636,0.01146669,0.9385613,0.001913488,0.00626408,0.00001971801],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9833136,0.002829048,0.005277535,0.0004694559,0.00006161757,0.00001739084,0.0009563665,0.0003298341,0.006745127],"genre_scores_gemma":[0.9944078,0.0004786891,0.0008419752,0.00002526977,0.00001359231,0.0000106912,0.0003972861,0.00005981107,0.003764878],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003482458,"threshold_uncertainty_score":0.01164997,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06856871122961135,"score_gpt":0.4069346975571455,"score_spread":0.3383659863275341,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}