{"id":"W4385347433","doi":"10.3390/md21080425","title":"Investigating A Multi-Domain Polyketide Synthase in Amphidinium carterae","year":2023,"lang":"en","type":"article","venue":"Marine Drugs","topic":"Protist diversity and phylogeny","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"National Centers for Coastal Ocean Science; National Oceanic and Atmospheric Administration; National Institutes of Health; National Science Foundation","keywords":"Cerulenin; Polyketide synthase; Biology; Dinoflagellate; Acyl carrier protein; Biochemistry; ATP synthase; Marine toxin; Fatty acid synthase; Toxin; Polyketide; Biosynthesis; Enzyme; Botany","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001277049,0.0001789716,0.0001678274,0.0002747528,0.000167443,0.0001834085,0.0001012006,0.0002667122,0.0002247316],"category_scores_gemma":[0.0001505744,0.0000907811,0.0002030754,0.0001799883,0.0001528932,0.0001731176,0.0002106594,0.00026794,0.000106215],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003202131,"about_ca_system_score_gemma":0.0002706141,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001890178,"about_ca_topic_score_gemma":0.002432749,"domain_scores_codex":[0.9999256,0.000007110648,0.000006168789,0.00002341606,0.00002098944,0.00001664966],"domain_scores_gemma":[0.9998611,0.00001719661,0.00004872845,0.000008652361,0.00002650785,0.00003779023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002982195,0.000005816066,0.001017374,0.00001650699,0.000002420431,0.00002387256,0.00001881823,0.00002429349,0.9984005,0.00002271674,0.000001917427,0.0004359287],"study_design_scores_gemma":[0.00001586696,0.0007183681,0.2002064,0.00001905854,0.00006251241,0.001249621,0.0005780604,0.00217333,0.7900337,0.0001692636,0.004750162,0.00002369592],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998517,0.000268381,0.000758449,0.00002470762,0.00000404894,0.000007618657,0.0001642107,0.00000576634,0.0002498339],"genre_scores_gemma":[0.9960045,0.0003162411,0.001925656,0.00003572127,0.000003880549,0.00001174873,0.0007497803,0.000006665238,0.0009458283],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001890178,"threshold_uncertainty_score":0.003758371,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01423746890736711,"score_gpt":0.2467863685710573,"score_spread":0.2325488996636902,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}