{"id":"W4385347433","doi":"10.3390/md21080425","title":"Investigating A Multi-Domain Polyketide Synthase in Amphidinium carterae","year":2023,"lang":"en","type":"article","venue":"Marine Drugs","topic":"Protist diversity and phylogeny","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"National Centers for Coastal Ocean Science; National Oceanic and Atmospheric Administration; National Institutes of Health; National Science Foundation","keywords":"Cerulenin; Polyketide synthase; Biology; Dinoflagellate; Acyl carrier protein; Biochemistry; ATP synthase; Marine toxin; Fatty acid synthase; Toxin; Polyketide; Biosynthesis; Enzyme; Botany","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002381479,0.0001169835,0.0001123786,0.00007930944,0.00006997646,0.00001791649,0.0001622166,0.00008820902,0.0000256009],"category_scores_gemma":[0.00009472188,0.0001304118,0.00005622221,0.0002252575,0.00006130082,0.000003105567,0.0004302064,0.00009845147,0.00008063478],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001477871,"about_ca_system_score_gemma":0.00004051815,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004425609,"about_ca_topic_score_gemma":0.0003229681,"domain_scores_codex":[0.9991638,0.0000649863,0.0001371652,0.0002765816,0.00008654388,0.0002709286],"domain_scores_gemma":[0.9996464,0.00001581794,0.00003695494,0.0001995301,0.00001667941,0.00008465014],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00004183299,0.00008117098,0.7131723,0.00005412195,0.00003461743,0.00006458568,0.0007949446,0.00004800425,0.2762741,0.0001266684,0.002850875,0.006456819],"study_design_scores_gemma":[0.003778343,0.0002261087,0.7934887,0.00006610529,0.00002060953,0.00002347354,0.001670897,0.001152397,0.1739572,0.001174713,0.02357105,0.0008703863],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977108,0.00003640568,0.00004869645,0.0003215552,0.000103877,0.000144297,0.00003260378,0.00003187086,0.001569843],"genre_scores_gemma":[0.9972439,0.00002658787,0.0008981227,0.0003918889,0.0001028499,0.00002167265,0.0002727561,0.00001440641,0.001027831],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1023169,"threshold_uncertainty_score":0.5318038,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01423746890736711,"score_gpt":0.2467863685710573,"score_spread":0.2325488996636902,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}