{"id":"W4385406156","doi":"10.1093/pcp/pcad086","title":"CRISPR/Cas9 Disruption of <i>MYB134</i> and <i>MYB115</i> in Transgenic Poplar Leads to Differential Reduction of Proanthocyanidin Synthesis in Roots and Leaves","year":2023,"lang":"en","type":"article","venue":"Plant and Cell Physiology","topic":"Plant Gene Expression Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; University of Victoria","keywords":"Proanthocyanidin; Transgene; CRISPR; Genetically modified crops; Biology; Reduction (mathematics); Botany; Chemistry; Genetics; Gene; Biochemistry; Polyphenol","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001073612,0.0005052219,0.0002448493,0.00020908,0.0001602896,0.0003159052,0.0003702394,0.0003222985,0.001507136],"category_scores_gemma":[0.0000760617,0.0002181638,0.0002274199,0.0001490555,0.0003229601,0.0001795367,0.0003215374,0.0008121518,0.0006778719],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002718629,"about_ca_system_score_gemma":0.0001748062,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000851637,"about_ca_topic_score_gemma":0.001359772,"domain_scores_codex":[0.9998459,0.00001337615,0.00001731493,0.00005665297,0.00003957679,0.00002717389],"domain_scores_gemma":[0.9998577,0.00002133705,0.00006026126,0.00001293416,0.000007721051,0.00003996656],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002528892,0.000005810647,0.00007534895,0.00002625843,0.000003530162,0.00002892446,0.000008603663,0.00003138724,0.999225,0.00008605498,0.00003947816,0.0004442785],"study_design_scores_gemma":[0.00001268407,0.0000443011,0.005040812,0.000007625352,0.00002008057,0.0003070584,0.00002681604,0.00141054,0.9861972,0.00006033218,0.006861515,0.00001101757],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9642905,0.0008403854,0.02695601,0.0001909606,0.00009023344,0.00007036092,0.002907556,0.001357774,0.003296167],"genre_scores_gemma":[0.9809973,0.0003920723,0.009402859,0.0001173366,0.00001148401,0.00007012515,0.002572429,0.0002936223,0.006142844],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001507136,"threshold_uncertainty_score":0.005041838,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008690148548827681,"score_gpt":0.2292938524498716,"score_spread":0.2206037039010439,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}