{"id":"W4385406156","doi":"10.1093/pcp/pcad086","title":"CRISPR/Cas9 Disruption of <i>MYB134</i> and <i>MYB115</i> in Transgenic Poplar Leads to Differential Reduction of Proanthocyanidin Synthesis in Roots and Leaves","year":2023,"lang":"en","type":"article","venue":"Plant and Cell Physiology","topic":"Plant Gene Expression Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; University of Victoria","keywords":"Proanthocyanidin; Transgene; CRISPR; Genetically modified crops; Biology; Reduction (mathematics); Botany; Chemistry; Genetics; Gene; Biochemistry; Polyphenol","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001189509,0.0001281676,0.0003069524,0.0001756328,0.00002249175,0.000004039116,0.00006088406,0.0001342257,0.000004008356],"category_scores_gemma":[0.00002100025,0.0001153197,0.00003609986,0.0001473254,0.00007369745,0.000005601304,0.00007109582,0.00006398153,6.976692e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003421467,"about_ca_system_score_gemma":0.00001250828,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006635813,"about_ca_topic_score_gemma":0.0001615844,"domain_scores_codex":[0.9990692,0.0001100184,0.0002508527,0.0003346049,0.00006125073,0.000174066],"domain_scores_gemma":[0.9997162,0.00003576508,0.00007469019,0.0001144143,0.0000130058,0.0000458974],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004134318,0.00006052104,0.004241135,0.000115102,0.00001554776,0.000001760909,0.0001720229,0.00004143957,0.9939371,0.000008004842,0.0003944317,0.000599455],"study_design_scores_gemma":[0.0004101951,0.0001480619,0.03802965,0.00004421436,0.00002999758,0.00001082009,0.0001987983,0.0001952099,0.9606331,0.00003887061,0.0001352055,0.0001258816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993215,0.0002689541,0.00001970581,0.00006520471,0.00003943488,0.000134227,0.000105942,0.000004984791,0.00004010652],"genre_scores_gemma":[0.9968714,0.002829312,0.00003730563,0.00001150549,0.00002885153,0.00001983124,0.0001340231,0.000008846042,0.00005899756],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03378851,"threshold_uncertainty_score":0.47026,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008690148548827681,"score_gpt":0.2292938524498716,"score_spread":0.2206037039010439,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}