{"id":"W4385423512","doi":"10.3390/biom13081193","title":"Nociceptor–Macrophage Interactions in Apical Periodontitis: How Biomolecules Link Inflammation with Pain","year":2023,"lang":"en","type":"review","venue":"Biomolecules","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Nociceptor; Inflammation; Trigeminal ganglion; Innate immune system; Periodontitis; Neuroscience; Immune system; Nociception; Medicine; Substance P; Neuropeptide; Immunology; Biology; Receptor; Sensory system; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004178086,0.0006093273,0.001428384,0.0007557319,0.0001004056,0.0001421572,0.0001868075,0.0003215562,0.0000642401],"category_scores_gemma":[0.0002627826,0.0004443203,0.0004216541,0.0009346993,0.0001351762,0.0001028119,0.00008697599,0.0004386016,0.0003373366],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003506457,"about_ca_system_score_gemma":0.0003134513,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001650413,"about_ca_topic_score_gemma":0.0005240199,"domain_scores_codex":[0.9974644,0.0004604203,0.0005503009,0.0006775327,0.000384966,0.0004623902],"domain_scores_gemma":[0.9987008,0.0001986747,0.000308404,0.0004947254,0.00008710871,0.0002102786],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003831081,0.0001591736,0.0000454188,0.008570961,0.0006497625,0.002819427,0.0001050608,1.48736e-7,0.000323509,0.0004337098,0.0002963431,0.9865582],"study_design_scores_gemma":[0.001369624,0.0005492238,0.0001393631,0.03590693,0.001305581,0.0003528711,0.0002137391,0.00008273526,0.0002839859,0.00004969108,0.9590291,0.0007171237],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001891015,0.9913623,0.004381381,0.001039114,0.0002781166,0.002012751,0.0001264053,0.0003104513,0.0003003778],"genre_scores_gemma":[0.0004268588,0.9907261,0.004466759,0.00007320555,0.0004077485,0.0006684962,0.001265061,0.0001911518,0.001774593],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.985841,"threshold_uncertainty_score":0.9998009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05904895148151337,"score_gpt":0.3540633801938881,"score_spread":0.2950144287123748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}