{"id":"W4385441753","doi":"10.1158/0008-5472.can-23-1387","title":"Turning Down the Temperature on Leukemia Stem Cells","year":2023,"lang":"en","type":"letter","venue":"Cancer Research","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Oxidative phosphorylation; Myeloid leukemia; Leukemia; Stem cell; Oxidative damage; Biology; Cell biology; Cancer research; Chemistry; Biochemistry; Oxidative stress; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001475123,0.0009017857,0.000779583,0.0003461153,0.001005397,0.00140353,0.0008936236,0.01068273,0.004493493],"category_scores_gemma":[0.006762973,0.0003304005,0.000751846,0.0002202694,0.001407459,0.001252977,0.000797189,0.01222204,0.005873766],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002205027,"about_ca_system_score_gemma":0.0006936095,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006672833,"about_ca_topic_score_gemma":0.0009918611,"domain_scores_codex":[0.9987607,0.0003010326,0.0001195287,0.0001801906,0.0004928521,0.0001457483],"domain_scores_gemma":[0.9974074,0.001496891,0.0001765634,0.00017839,0.0004623242,0.000278509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005414342,0.0001037455,0.001077675,0.0002609961,0.00004169753,0.005211525,0.0001210298,0.0002086662,0.01388502,0.006497552,0.8985982,0.07345251],"study_design_scores_gemma":[0.0002575154,0.0003670148,0.002898683,0.000208056,0.00004826211,0.003733255,0.0001911782,0.0006941013,0.009829215,0.01106583,0.9706614,0.00004551072],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.008156454,0.01697979,0.001137757,0.8391955,0.1203651,0.00005737855,0.0002149695,0.0003574076,0.01353552],"genre_scores_gemma":[0.05027671,0.01781713,0.001035067,0.7179486,0.1858873,0.0001357364,0.0001233968,0.0001095041,0.02666661],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01068273,"threshold_uncertainty_score":0.01599866,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06263608491944518,"score_gpt":0.3479633964372599,"score_spread":0.2853273115178148,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}