{"id":"W4385442394","doi":"10.1007/978-3-031-34567-8_11","title":"Regulatory Oversight of Cell, Tissue, and Gene Therapy Products in Singapore","year":2023,"lang":"en","type":"article","venue":"Advances in experimental medicine and biology","topic":"Biomedical Ethics and Regulation","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Health Canada","keywords":"Legislation; Regulatory authority; Business; Product (mathematics); Gene technology; Quality (philosophy); Risk analysis (engineering); Medicine; Biotechnology; Political science; Public administration; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000205869,0.00008502794,0.000255554,0.0001822342,0.00001798113,6.365381e-7,0.00002651516,0.0001170338,0.0000201337],"category_scores_gemma":[0.00002406507,0.00005515435,0.000007558576,0.0002911811,0.001091775,0.00004696702,0.00003175107,0.0001050208,4.451715e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001486888,"about_ca_system_score_gemma":0.00002016542,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003677075,"about_ca_topic_score_gemma":0.000006327542,"domain_scores_codex":[0.9993266,0.00003270704,0.0002141315,0.000216551,0.00008010007,0.0001298799],"domain_scores_gemma":[0.9997366,0.00005767098,0.00005344653,0.00008723086,0.00001750188,0.00004751348],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001409161,0.00007898816,0.007543834,0.00007586171,0.00000410837,0.00001515748,0.001327368,3.444008e-7,0.9579763,0.0009491912,0.00005085445,0.03183712],"study_design_scores_gemma":[0.005109621,0.002659438,0.04263265,0.0002776969,0.000007108753,0.0000355506,0.002539087,0.00007905433,0.9118032,0.00246259,0.03226057,0.0001333679],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9166172,0.07874347,0.000003292775,0.003766908,0.0001750126,0.0001931123,0.00000110674,0.0000110309,0.0004889349],"genre_scores_gemma":[0.9784393,0.02071884,0.0002874409,0.0003336571,0.0001015978,0.000007645788,0.00003792056,0.00000568149,0.00006792987],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06182216,"threshold_uncertainty_score":0.4022692,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0449927443280369,"score_gpt":0.3777771782872508,"score_spread":0.3327844339592139,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}